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. 2022 Feb 4;2022:7858477. doi: 10.1155/2022/7858477

Figure 2.

Figure 2

Development of a hypoxia-derived risk score for GBM prognosis in TCGA dataset. (a) LASSO regression results with the minimum lambda of 0.1273. (b) LASSO regression profiles. (c) Univariate cox regression analysis was presented for the associations of candidate variables with GBM prognosis. (d) Heat map visualized the expression of candidate variables ALDH3B1 and CTSZ in high- and low-risk patients. (e, f) The mRNA expression of ALDH3B1 and CTSZ was compared in GBM and normal tissues. (g) Distribution of risk score across GBM patients. GBM patients were clustered into high- and low-risk groups in line with the median value. (h) Distribution of alive and dead status in high- and low-risk groups. (i) Distribution of disease-free and recurrence/progression in high- and low-risk groups.