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. 2022 Feb 4;2022:7858477. doi: 10.1155/2022/7858477

Table 2.

Univariate cox regression and ROC analysis of genes in the hypoxia-related module across GBM patients in TCGA dataset.

AUC
Gene P value HR 3 years 4 years 5 years 6 years 7 years
CTSZ 0.001401 1.001996 0.541868 0.531175 0.519589 0.70724 0.70724
IL4I1 0.003412 1.043224 0.599506 0.519613 0.466411 0.582664 0.582664
P2RY6 0.004204 1.076029 0.415884 0.389919 0.394214 0.295217 0.295217
ALDH3B1 0.004547 1.020909 0.581294 0.60466 0.668369 0.8329 0.8329
SERPINA1 0.006526 1.002752 0.597413 0.562337 0.556287 0.677964 0.677964
CTSC 0.009301 1.002576 0.503505 0.493347 0.480802 0.576349 0.576349
OSCAR 0.011524 1.040114 0.508397 0.410077 0.503492 0.577863 0.577863
RAC2 0.011789 1.019221 0.551351 0.436907 0.345869 0.451122 0.451122
PTPN7 0.01985 1.047849 0.594861 0.581799 0.528553 0.801346 0.801346
DOK3 0.019975 1.017264 0.566994 0.611672 0.483944 0.664192 0.664192
FCGR2A 0.02197 1.002868 0.644756 0.503723 0.55335 0.742644 0.742644
NCF2 0.02279 1.012677 0.562694 0.454037 0.535923 0.609302 0.609302
APOBR 0.025558 1.036254 0.531441 0.574135 0.629578 0.885046 0.885046
SPP1 0.030952 1.000044 0.581509 0.308017 0.164882 0.188879 0.188879
NOD2 0.033034 1.051209 0.617333 0.696306 0.666013 0.566436 0.566436
DENND2D 0.034141 1.02575 0.569936 0.422816 0.401108 0.495169 0.495169
TYMP 0.036372 1.005606 0.599976 0.543437 0.613858 0.827708 0.827708
HMOX1 0.03984 1.000692 0.49011 0.418883 0.242794 0.263565 0.263565
DAB2 0.042431 1.004009 0.496005 0.448426 0.503731 0.644549 0.644549
FPR3 0.044063 1.010057 0.566919 0.414651 0.405434 0.526891 0.526891
FGR 0.045493 1.017681 0.632235 0.47959 0.595887 0.70649 0.70649
CD180 0.049196 1.023759 0.485978 0.302002 0.326194 0.362863 0.362863
FBP1 0.049958 1.020177 0.656886 0.511191 0.47078 0.518965 0.518965

Abbreviations: HR: hazard ratio; AUC: area under the curve.