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. 2022 Jan 18;44(1):101–113. doi: 10.1007/s00281-021-00902-8

Table 2.

Putative causal variants with PIP > 95% for autoimmune disorders. See Table 1 for trait abbreviations

Trait Variant Gene Function PIP
CD rs2066844 NOD2 R702W 99.9%
CD rs2066845 NOD2 G908R 99.9%
CD rs5743293 NOD2 Fs1007insC 99.9%
CD rs61839660 IL2RA Intronic 99.9%
CD rs7307562 LRRK2 Intronic 99.9%
CD rs5743271 NOD2 N289S 99.3%
CD rs72796367 NOD2 Intronic 98.3%
CD rs41313262 IL23R V362I 97.3%
CD rs28701841 PRDM1 Intergenic 97.1%
UC rs6017342 HNF4A Intergenic 99.9%
UC rs35667974 IFIH1 I923V 99.4%
UC rs4676408 GPR35 Intergenic 99.4%
IBD rs6062496 RTEL1-TNFRSF6B Intronic 99.6%
IBD rs141992399 CARD9 1434 + 1G > C 99.5%
IBD rs74465132 IKZF1 Intergenic 99.4%
IBD rs10748781 NKX2-3 Intergenic 99.0%
IBD rs35874463 SMAD3 I170V 98.9%
IBD rs1887428 JAK2 Intergenic 97.4%
SLE rs2736100 TERT Intronic 100.0%
SLE rs2431697 PTTG1-MIR146A Intergenic 99.9%
SLE rs2297550 IKBKE TF binding site 99.7%
SLE rs7097397 WDFY4 Arg1816Gln 99.3%
SLE rs2205960 TNFSF4 Intergenic 95.7%
T1D rs34536443 TYK2 P1104A 100.0%
MS rs533259 RNASEL Intronic 100.0%
MS rs733724 HACE1 Intronic 98.0%
PSOR rs17716942 KCNH7 Intronic 100.0%
PSOR rs12188300 IL12B Intergenic 100.0%
PSOR rs33980500 TRAF3IP2-AS1 D10N 100.0%
PSOR rs11795343 DDX58 Intronic 99.7%
PSOR rs8016947 NFKBIA Intergenic 100.0%
PSOR rs28998802 NOS2 Intronic 100.0%
PSOR rs34536443 TYK2 P1104A 99.6%%
CeD rs1893592 UBASH3A Intronic 98.0%