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. Author manuscript; available in PMC: 2022 Mar 1.
Published in final edited form as: Med Res Rev. 2021 Oct 11;42(2):710–743. doi: 10.1002/med.21859

FIGURE 1.

FIGURE 1

Schematic diagram of BRD4 domain features and crystal structures. (A) Domain architecture of three BRD4 protein isoforms. (B) Crystal structure of BRD4(1) (PDB ID: 3MXF). (C) Crystal structure of BRD4(2) (PDB ID: 5U2C). (D) NMR structure of the BRD4 ET domain (PDB ID: 6BNH). Protein is represented by blue ribbons with WPF shelf residues indicated by yellow sticks