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. Author manuscript; available in PMC: 2023 Mar 1.
Published in final edited form as: Cancer. 2021 Nov 11;128(5):1101–1109. doi: 10.1002/cncr.34010

Table 2:

Adjusted Mean Difference in the Number and Quality of Conversations about Aging-Related Concerns in Pre-Frail and Frail vs Robust Patients and Usual-Care vs GA-Intervention Patients

Adjusted Mean Difference in Pre-Frail and Frail compared to Robust Patients
Adjusted Mean Difference in GA-Intervention compared to Usual-Care in Robust, Pre-Frail, and Frail Patients pValue of Interaction (frailty status*study arm)
Usual-Care GA-Intervention

Difference (95% CI) pValue Difference (95% CI) pValue Difference (95% CI) pValue
# Conversations Robust ref - ref - 3.27 (1.68 to 4.86) 0.0002
Pre-Frail 0.83 (−0.21 to 1.87) 0.1197 1.31 (0.37 to 2.25) 0.0067 3.75 (2.32 to 5.18) 0.0001 0.6111
Frail 1.73 (0.59 to 2.87) 0.0031 2.49 (1.51 to 3.47) <0.0001 4.03 (2.50 to 5.56) 0.0001

# Concerns Acknowledged Robust ref - ref - 2.08 (1.04 to 3.12) 0.0002
Pre-Frail 0.79 (−0.03 to 1.61) 0.0624 0.58 (−0.13 to 1.29) 0.1077 1.87 (0.97 to 2.77) 0.0002 0.7397
Frail 1.12 (0.24 to 2.00) 0.0145 1.31 (0.56 to 2.06) 0.0006 2.27 (1.29 to 3.25) <0.0001

# Concerns Addressed Robust ref - ref - 2.03 (0.87 to 3.19) 0.0013
Pre-Frail 0.2 (−0.41 to 0.81) 0.5232 0.3 (−0.23 to 0.83) 0.2634 2.13 (1.05 to 3.21) 0.0005 0.9403
Frail 0.71 (0.04 to 1.38) 0.0382 0.87 (0.32 to 1.42) 0.0021 2.19 (1.07 to 3.31) 0.0005

Geriatric Assessment (GA), Confidence Intervals (CI)

Models included the study arm, frailty status, and interaction term between frailty status and study arm as a fixed effect and practice site as a random effect independent of residual error