Table 2.

Summary of Meta-Analysis

	Patients (n) with Delirium/Group (%)	RR [95% CI]	p-value
Supra- vs. Infra-tentorial Strokes (n=10)
Supratentorial	605/2447 (24.7%)	2.01 [1.49, 2.71]	0.001
Infratentorial	53/530 (10.0%)	1
Anterior vs. Posterior Territory Strokes (n=18)
Anterior	722/3061 (23.6%)	1.41 [1.13, 1.78]	0.005
Posterior	152/1030 (14.8%)	1
Cortical vs. Subcortical Strokes (n=8)
Cortical	262/1080 (24.3%)	1.54 [1.25, 1.89]	0.019
Subcortical	185/1115 (16.6%)	1
Right vs. Left Sided Strokes (n=18)
Right	391/1574 (24.8%)	0.99 [0.77, 1.28]	0.740
Left	410/1870 (21.9%)	1
OCSP Vascular Classification (n=11)
Total anterior circulation infarct (TACI)	162/556 (29.1)	3.95 [2.57, 6.15]	<0.05
Partial anterior circulation infarct (PACI)	99/629 (15.7)	1.50 [0.95, 2.35]	ns
Posterior circulation infarct (POCI)	49/448 (10.9)	1.25 [0.76, 2.01]	ns
Lacunar Infarct (LACI)	65/977 (6.7)	1	Ref
TOAST Classifications (n=5)
Cardioembolic	86/246 (35.0%)	2.69 [1.75, 4.51]	<0.05<0.05Ref
Large Vessel	123/355 (34.6%)	2.57 [1.58, 4.02]
Small Vessel	58/422 (13.7%)	1
Hemorrhagic vs. Ischemic Strokes (n=9)
Hemorrhagic	198/578 (34.2%)	1.74 [1.42, 2.11]	<0.05
Subarachnoid	21/66 (31.8%)	1.52 [0.83, 2.31]	ns
Ischemic	641/3326 (19.3%)	1	Ref
Qualitative Atrophy (n=2)
Present	37/199 (18.6%)	1.66 [1.12, 2.27]	0.031
Absent	7/71 (9.9%)	1
Leukoaraiosis (n=4)
Present	115/629 (18.3%)	1.33 [0.58; 3.01]	0.353
Absent	41/298 (13.8%)	1

The relative risk (RR) of delirium according to different types or localizations of strokes were calculated using random-effects models (ns = not significant, i.e. p>0.05). Ref = reference, to clarify the reference group against which all other groups were compared for the purposes of this table in network meta-analyses across 3 or more groups. In all other cases, an RR value of 1 indicates the reference group.