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. Author manuscript; available in PMC: 2023 Feb 10.
Published in final edited form as: Neuroscience. 2021 Dec 16;483:40–51. doi: 10.1016/j.neuroscience.2021.12.016

Figure 3. Partial agonism of α7 nAchRs does not affect nicotine-induced NAc DA.

Figure 3.

(A) Average ΔF/F of GRAB-DA signals of mice during an intraperitoneal injection of nicotine (1.5 mg/kg) 10 min after a pretreatment of IP GTS 21 (4 mg/kg) or saline (0.9%). Signals are aligned to the second IP injection. Green, GTS 21; grey, saline. Green area represents duration of fiber photometry recording. (B) Mean ΔF/F (3 min bins) of GRAB-DA signals shown in (A) (n=6/group, two-way repeated measures ANOVA). Dark lines represent means and lighter, shaded areas represent SEM. See Table S1 for details on statistical analyses.