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. Author manuscript; available in PMC: 2023 Feb 10.
Published in final edited form as: Neuroscience. 2021 Dec 16;483:40–51. doi: 10.1016/j.neuroscience.2021.12.016

Figure 8. Partial agonism of α7 nAchRs does not affect food-evoked NAc DA.

Figure 8.

(A) Average ΔF/F of GRAB-DA signals of 24 h food-deprived mice given a pellet of chow 10 min after a pretreatment with intraperitoneal (IP) GTS 21 (4 mg/kg) or saline (0.9%). Signals are aligned to food presentation. Green, GTS 21; grey, saline. Dark lines represent means and lighter, shaded areas represent SEM. (B) Maximum ΔF/F of the GRAB-DA signal shown in (A) (n=8/group, paired t-test). (C) Mean ΔF/F of the GRAB-DA signal shown in (A) (n=8/group, paired t-test). For box and whisker plots, the box extends from the 25th to 75th percentiles, the line in the box represents the median, and the whiskers extend from the maximum to minimum values. Grey circles represent individual mice. See Table S1 for details on statistical analyses.