TABLE 1.
Reagents and conditions for enantioselective synthesis of 4-ATQs: aldehyde 4 (1 equiv.), amine 2 (1 equiv.), N-vinylcarbamate 3 (1.1 equiv.), and catalyst 1 (0.1 equiv.) in CH2Cl2 (0.1 M).
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Enantiomeric ratio (er) was determined by SFC or HPLC.