Table 4.
Effect of crude extracts of Ac on B.W & plasma potassium of cisplatin-treated rats.
| Body Weight (g) | Observation (Day) | |||
|---|---|---|---|---|
| Groups | 0 | 7 | 14 | 21 |
| A. camelorum (Ac) | ||||
| Control | 264 ± 9.7 | 286 ± 10.4 | 348 ± 10.2 | 326 ± 10.7 |
| Cis | 268 ± 9.3 | 206 ± 10.1 (*) | 209 ± 11 (*) | 184 ± 10.6 (*) |
| Cis + Aca | 287 ± 10.6 | 230 ± 9.3 (&) | 267 ± 10.8 (&) | 250 ± 12 (&) |
| Cis + Acb | 289 ± 10.8 | 240 ± 7.7 (#) | 304 ± 10.6 (#) | 289 ± 10.3 (#) |
| Plasma potassium (mEq/L) | ||||
| Control | 8.3 ± 0.58 | 7.9 ± 0.69 | 8.5 ± 0.58 | 8.3 ± 0.48 |
| Cis | 8.0 ± 0.32 | 3.1 ± 0.44 (*) | 4.6 ± 0.45 (*) | 4.6± 0.52 (*) |
| Cis + Aca | 8.0 ± 0.66 | 5.5 ± 0.46 (&) | 5.8 ±0.48 (&) | 5.1 ± 0.35 (&) |
| Cis + Acb | 8.3 ± 0.47 | 6.7 ± 0.44 (#) | 6.3± 0.53 (#) | 7.2 ± 0.57 (#) |
Mean ± SEM (n = 6), where Cis is cisplatin (5 mg/kg i.p), Cis + Aca is cisplatin + Alhagi camelorum extract (400 mg/kg/21 days), Cis + Acb is cisplatin + Alhagi camelorum extract (600 mg/kg/21 days. The results are considered significant (*) if p < 0.005. * p < 0.05 vs. normal control, & p < 0.05 vs. cisplatin, and # p < 0.05 vs. cisplatin + Alhagi camelorum on corresponding days.