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NIR-II light-responsive semiconducting polymer nanoadjuvant (SPNIIR) is designed and applied for synergetic photothermal immunotherapy, not only to the primary and distant tumors but also the metastasis in the lung [37]. PTT, photothermal therapy; TLR, toll-like receptor; DC, dendritic cell; R848, a TLR agonist; TAA, tumor-associated antigens; ATP, adenosine triphosphate; CRT, calreticulin; HMGB1, high mobility group box 1 protein.
