Table 2.
Determination of MIC (minimum inhibition concentration) and MBC (minimum bactericidal concentration) of manuka oil against the five bacterial species, and the diameter changes of inhibition-zone in disc diffusion test according to increase of concentration.
| <Manuka Oil> | MIC | MBC | Inhibition Zone Diameter (mm) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Concentration (%) | 20.00 | 10.00 | 5.00 | 2.50 | 1.25 | 0.63 | 0.31 | 0.16 | 0.08 | 0.04 | 0.02 | 0.00 | ||
| Streptococcus mutans | 0.08 | 2.5 | 12.4 | 10.4 | 9.2 | 8.7 | 6.5 | 2.2 | 1.3 | - | - | - | - | - |
| Streptococcus anginosus | 0.08 | 0.31 | 12.3 | 11.2 | 10.7 | 9.9 | 8.8 | 7.5 | 5.1 | 4.2 | 1.4 | - | - | - |
| Staphylococcus epidermidis | 0.02 | 0.31 | 10.9 | 9.2 | 8.2 | 7.4 | 6.0 | 4.2 | 3.1 | 2.3 | 1.7 | 0.6 | - | - |
| Porphyromonas gingivalis | 0.16 | 1.25 | 25< | 25< | 25< | 25< | 6.9 | 5.1 | 4.8 | 2.6 | 1.5 | - | - | - |
| Escherichia coli | 1.25 | 10.0 | 4.2 | 2.3 | 1.4 | - | - | - | - | - | - | - | - | - |