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. 2001 Oct;39(10):3512–3519. doi: 10.1128/JCM.39.10.3512-3519.2001

TABLE 3.

Genotype- and subgenotype-specific residue substitutions in deduced F0 protein sequences

Genotype and subgenotype Medium % of similaritya Range of similarity (%)a Consensus residue and its position in deduced F0 protein sequences
52 (I) 69 (M) 82 (E) 93 (T) 101 (R) 104 (G) 107 (S) 118 (I) 121 (I) 124 (S) 176 (A) 192 (N) 195 (Q) 272 (N) 288 (T) 314 (F) 341 (T) 396 (M) 482 (E)
I 96.5 (94.9–98.1) j Ec Td G K
II 97.6 (95.0–99.7) L Db E T G K
III 91.2 (88.8–94.7) E T
IV 97.3 (94.4–97.9) E T
V (100) T Ve
VI 94.6 (90.9–99.5)
 a 98.4 (96.8–99.5) T
 ce
 d 98.4 (94.7–99.7) S
 b 95.4 (93.0–97.7) R N Ii A
VIII 91.2 (90.4–92.0) T R Y N Sh A
VII 92.1 (86.6–99.2)
 b 97.4 (95.7–99.2) Vf g
 a 98.7 (91.7–100) K V S R Y N S I A
 c 94.9 (89.6–95.5) K V S R Y N S I A
 d 96.3 (95.5–99.2) V K V S R Y N Y S I A
a

The median genetic distance between the strain on top of the genotype or subgenotype and other strains in the same group is used as the median percentage of sequence similarity. 

b

D-for-E substitution is shared by TW/69 and TW/95-3 in genotype III. 

c

Residue E is retained in AE 232/1/96 of genotype VIIb. 

d

Residue T is not retained in ZA-5/68 of genotype VIII or in TW/69 and TW/95-3 of genotype III. 

e

Only one value was obtained, so no median or range is given. 

e V-for-I substitution is shared by ZA-5/68 grouped in genotype VIII. 

f

V-for-I substitution in genotype VII is shared by TW/69 and TW/95-3 in genotype III and AF2240 in genotype VIII. 

g

No complete sequence of the F genes is available. 

h

S-for-T substitution is shared by GB 1168/84 in genotype VIb. 

i

I-for-M substitution is shared by Ch-F48E9/44 in genotype III. 

j

—, genetic identity with the consensus.