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. 2022 Feb 6;27(3):1086. doi: 10.3390/molecules27031086

Table 2.

Determination of release kinetics of CPT from liposomes.

Formulation Code Higuchi Korsmeyer- Peppas Zero Order First Order Hixson-Crowell
r2 AIC r2 n Value AIC r2 k0 (h−1) AIC r2 K1 (h−1) AIC r2 n Value AIC
F4 0.994 35.14 0.998 0.312 40.95 0.984 4.98 47.56 0.991 0.122 42.74 0.996 0.133 51.89
F8 0.990 35.36 0.996 0.288 38.45 0.961 6.88 47.13 0.997 0.098 42.59 0.998 0.145 50.36
F12 0.993 34.35 0.994 0.291 38.23 0.984 7.45 45.92 0.989 0.112 40.25 0.996 0.125 49.75

Note: r2 denotes coefficient of determination; AIC denotes Akaike information criterion; k0 denotes zero order release constant; K1 denotes first order release constant; n denotes diffusion release exponent.