Table 4.
Physical stability analysis (particle size, PDI, and zeta potential) of CPT-containing liposomes.
| Formulation Code | Mean Particle Diameter (µm) |
Mean Particle Diameter After 30 Days (µm) | Poly Dispersity Index (PDI) | PDI after 30 Days | Zeta Potential (mV) | Zeta Potential after 30 Days (mV) | |||
|---|---|---|---|---|---|---|---|---|---|
| Initial | RT | 2–8 °C | Initial | RT | 2–8 °C | Initial | RT | 2–8 °C | |
| F4 | 0.498 ± 0.16 | 0.71 ± 0.1 | 0.62 ± 0.11 | 0.29 ± 0.03 | 0.54 ± 0.01 | 0.40 ± 0.01 | −20.2 ± 0.9 | −17.9 ± 1.9 | −18.8 ± 0.8 |
| F8 | 0.234 ± 0.19 | 0.45 ± 0.02 | 0.24 ± 0.1 | 0.47 ± 0.06 | 0.58 ± 0.08 | 0.49 ± 0.05 | −23.86 ± 1.8 | −22.11 ± 2.1 | −22.85 ± 1.3 |
| F12 | 0.168 ± 0.09 | 0.29 ± 0.05 | 0.19 ± 0.09 | 0.28 ± 0.09 | 0.39 ± 0.08 | 0.28 ± 0.08 | −27.05 ± 0.8 | −25.18 ± 0.8 | −27.01 ± 0.6 |
Data are given as mean ± SD (n = 3).