Fatty acid composition of liver mitochondria: (A) Membrane fatty acid composition (mol% of total mitochondrial lipids) in mitochondria isolated from the liver of WT and Elovl2 KO mice. Bars are means ± SEM from 6 different mitochondrial preparations for each mouse genotype. Values of mean, standard deviations (SD), SEM and P are shown in Supplementary Table S1. (B) Relative amount (mol% of total mitochondrial lipids) of different types of fatty acids: saturated fatty acids (SFA), unsaturated fatty acids (UFA), monounsaturated fatty acids (MUFA), and polyunsaturated fatty acids (PUFA). (C) Double bond index (DBI) in membrane fatty acids. In B and C, individual values are displayed in bars with means ± SEM from 6 different mitochondrial preparations for each mouse genotype. Significant differences are shown between WT and Elovl2 KO mice: * p < 0.05, ** p < 0.01, *** p < 0.001.