Table 4.

Inhibition of COX-1 and COX-2 activity of A. acutiloba aerial parts and roots extracts.

	COX-1 Inibition [%] ±SD		COX-2 Inhibition [%] ±SD
Extract	50 µg/mL	100 µg/mL	50 µg/mL	100 µg/mL
AH	50.17 ± 0.85	71.32 ± 2.73	43.65 ± 1.36	78.52 ± 2.18
AR	31.27 ± 0.76	47.80 ± 1.12	48.59 ± 2.19	54.25 ± 1.23
AH-B	76.82 ± 0.69	83.14 ± 1.08	79.75 ± 1.29	95.10 ± 1.81
AR-B	63.17 ± 1.28	78.29 ± 2.25	72.64 ± 1.93	90.93 ± 2.65
AH-O	52.65 ± 2.19	74.50 ± 1.29	60.23 ± 0.67	80.12 ± 1.73
AR-O	45.73 ± 1.45	64.49 ± 2.74	58.08 ± 1.79	79.15 ± 3.10
AH-E	nd	10.43 ± 0.19	nd	28.09 ± 0.13
AR-E	nd	28.71 ± 0.35	nd	41.96 ± 1.30

AH—60% methanolic extract of the aerial parts, AR—60% methanolic extract of the roots, AH-B—butanol fraction from the aerial parts, AR-B—butanol fraction from the roots, AH-O—ethyl acetate fraction from the aerial parts, AR-O—ethyl acetate fraction from the roots, AH-E—diethyl ether fraction from the aerial parts, AR-E—diethyl ether fraction from the roots. Indomethacin (5 µM)—78.65 ± 1.28% (COX-1); 91.07 ± 2.45% (COX-2)].