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. 2022 Feb 2;27(3):1009. doi: 10.3390/molecules27031009

Scheme 1.

Scheme 1

The synthesis of target compounds 6~37. Reagents and conditions: (a) DMF, r.t., 5 h; (b) ethyl acetate, reflux, 3 h; (c) CH3CN, r.t., 4 h, 15 W LED; (d) reflux, 4 h; (e) NaOH, DMF, r.t., 5 h; (f) DCM, 0 °C ~ r.t., 6 h, N2 atomosphere; (g) K2CO3, anhydrous acetone, reflux, 2 h.