Table 2.
IC50 values of synthesized compounds in different cancer cell lines. Data are presented as mean ± SD (n = 3).
| Compounds | IC50 (µg/mL) | |||
|---|---|---|---|---|
| HepG-2 | Panc-1 | BxPC-3 | HPDE | |
| 9a | 10.96 ± 2.39 | 11.95 ± 0.76 | 14.39 ± 0.73 | >50 mg/mL |
| 9b | 8.53 ± 1.10 | 13.63 ± 1.16 | 14.88 ± 4.19 | >50 mg/mL |
| 9c | 19.08 ± 3.23 | 15.13 ± 4.13 | 21.47 ± 1.08 | >50 mg/mL |
| 9d | 22.71 ± 2.30 | 25.32 ± 1.91 | 18.05 ± 3.56 | >50 mg/mL |
| 9e | 15.04 ± 2.89 | 12.15 ± 1.29 | 13.28 ± 1.57 | >50 mg/mL |
| 9f | 6.39 ± 1.25 | 12.60 ± 1.20 | 14.18 ± 1.87 | >50 mg/mL |
| 9g | 32.53 ± 1.45 | 29.26 ± 4.23 | 25.70 ± 4.89 | >50 mg/mL |
| 9h | 17.34 ± 0.96 | 14.72 ± 2.87 | 12.60 ± 0.62 | >50 mg/mL |
| 9i | 27.017 ± 5.32 | 16.13 ± 1.820 | 21.83 ± 2.98 | >50 mg/mL |
| 9j | 25.54 ± 0.144 | 16.04 ± 3.18 | 21.42 ± 2.15 | >50 mg/mL |
| 9k | 33.11 ± 5.12 | 19.878 ± 3.35 | 7.27 ± 1.49 | >50 mg/mL |
| Doxorubicin | 5.11 ± 0.98 | 6.90 ± 0.93 | 7.31 ± 1.12 | >50 mg/mL |