Table 5.
Changes in the lipid profile at 6 weeks after treatments by categories of variables according to the median value at baseline.
| Intervention | ||||||||
|---|---|---|---|---|---|---|---|---|
| Variable | ABG | Placebo | Change Intertreatments | |||||
| Baseline | Change | P for Trend | Baseline | Change | P for Trend | Mean (95% CI) | p-Value | |
| Total cholesterol, mg/dL | ||||||||
| Global | 243 ± 32 | 0.865 (−4.1; −5.9) |
0.047 † | 240 ± 30 | 2.15 (−3.1; 7.4) |
0.421 * | −1.29 (−8.6; 6.0) |
0.727 |
| ≤242 mg/dL | 219 ± 19 | 5.52 (−1.3; 12) |
0.028 † | 218 ± 22 | 6.90 (−1.9; 18) |
0.120 * | 0.914 (−8.7; 10) |
0.849 |
| >242 mg/dL | 267 ± 24 | −3.94 (−11; 3.4) |
0.283 * | 263 ± 21 | −0.329 (−8.6; 8.0) |
0.872 † | −3.49 (−7.7; 15) |
0.535 |
| LDLd, mg/dL | ||||||||
| Global | 165 ± 24 | −0.390 (−4.1; 3.3) |
0.011 † | 165 ± 22 | 0.560 (−4.8; 3.7) |
0.279 † | 0.156 (−5.8; 5.5) |
0.956 |
| ≤166 mg/dL | 151 ± 14 | 3.33 (−1.1; 7.6) |
0.143 * | 147 ± 19 | 0.718 (−4.7; 6.1) |
0.131 † | 2.69 (−9.6; 4.2) |
0.438 |
| >166 mg/dL | 188 ± 17 | −8.20 ‡ (−15; −1.6) |
0.017 * 0.014 † |
182 ± 18 | −2.55 (−9.8; 4.7) |
0.475 † | −6.28 (−16; 3.1) |
0.184 |
| LDL (Friedewald), mg/dL | ||||||||
| Global | 162 ± 26 | 1.47 (−2.7; 5.6) |
0.049 † | 161 ± 25 | 1.91 (−3.3; 7.2) |
0.308 † | −0.258 (−6.6; 7.1) |
0.941 |
| ≤162 mg/dL | 148± 17 | 4.50 (−0.41; 9.41) |
0.071 * | 148 ± 19 | 4.11 (−2.6; 11) |
0.221 * | 0.729 (−7.9; 9.3) |
0.866 |
| >162 mg/dL | 186 ± 18 | −3.79 (−11; 3.7) |
0.063 † | 184 ± 17 | −1.99 (−11; 6.9) |
0.607 † | −1.85 (−13; 9.5) |
0.744 |
| HDL, mg/dL | ||||||||
| Global | 56.9 ± 11.4 | 0.005 (−0.99; 1.0) |
0.354 † | 55.0 ± 10.9 | 1.02 (−0.41; 2.5) |
0.159 * | −0.695 (−2.5; 1.1) |
0.492 |
| ≤55.5 mg/dL | 49.3 ± 7.86 | −0.045 (−1.4; 1.3) |
0.136 † | 48.2 ± 7.23 | 1.01 (−0.90; 2.9) |
0.124 † | −1.49 (−3.7; 0.70) |
0.178 |
| >55.5 mg/dL | 65.3 ± 8.32 | 0.061 (−1.4; 1.6) |
0.816 † | 62.8 ± 9.19 | 1.04 (−1.2; 3.3) |
0.360 * | 0.105 (−2.9; 3.1) |
0.945 |
| Total Cholesterol/ HDL | ||||||||
| Global | 4.41 ± 0.92 | 0.006 (−0.09; 0.10) |
0.008 † | 4.48 ± 0.82 | −0.023 (−0.16; 0.12) |
0.239 † | 0.033 (−0.13; 0.20) |
0.694 |
| ≤4.44 | 3.73 ± 0.45 | 0.062 (−0.03; 0.16) |
0.200 * | 3.86 ± 0.51 | −0.022 (−0.22; 0.18) |
0.358 † | 0.074 (−0.15; 0.29) |
0.506 |
| >4.44 | 5.10 ± 0.74 | −0.052 (−0.22; 0.12) |
0.004 † | 5.06 ± 0.60 | −0.024 (−0.23; 0.18) |
0.443 † | −0.023 (−0.30; 0.25) |
0.864 |
| LDLd/HDL | ||||||||
| Global | 3.02 ± 0.72 | −0.013 (−0.08; 0.05) |
0.001 † | 3.09 ± 0.64 | −0.049 (−0.15; 0.05) |
0.168 † | 0.156 (−5.8; 5.5) |
0.956 |
| ≤3.07 | 2.47 ± 0.33 | 0.065 (−0.01; 0.14) |
0.105 * | 2.60 ± 0.41 | −0.120 (−0.25; 0.07) |
0.062 * | 0.077 (−0.09; 0.24) |
0.362 |
| >3.07 | 3.58 ± 0.58 | −0.114 (−0.24; 0.01) |
0.071 * 0.002 † |
3.55 ± 0.46 | 0.019 (−0.14; 0.18) |
0.356 † | −0.05 (−0.21; 0.16) |
0.782 |
| LDL(Fried)/HDL | ||||||||
| Global | 2.95 ± 0.72 | 0.038 (−0.04; 0.12) |
0.002 † | 3.00 ± 0.63 | 0.001 (−0.11; 0.11) |
0.089 † | 0.041 (−0.09; 0.18) |
0.551 |
| ≤2.94 | 2.43 ± 0.40 | 0.072 (−0.01; 0.15) |
0.084 † | 2.52 ± 0.41 | −0.036 (−0.19; 0.12) |
0.154 † | 0.089 (−0.09; 0.27) |
0.319 |
| >2.94 | 3.49 ± 0.56 | −0.021 (−0.15; 0.11) |
0.002 † |
3.45 ± 0.45 | 0.035 (−0.14; 0.21) |
0.280 † | −0.021 (−0.22; 0.18) |
0.840 |
| TG (log), mg/dL | ||||||||
| Global | 2.04 ± 0.18 | −0.031 ‡ (−0.06; − 0.001) |
0.042 * | 2.05 ± 0.19 | −0.016 (−0.05; 0.02) |
0.419 * | −0.016 (−0.03; 0.06) |
0.531 |
| ≤2.00 | 1.90 ± 0.09 | −0.011 (−0.05; 0.03) |
0.568 * | 1.91 ± 0.09 | 0.024 (−0.04; 0.09) |
0.438 * | −0.021 (−0.10; 0.06) |
0.603 |
| >2.00 | 2.16 ± 0.15 | −0.049 (−0.09; −0.002) |
0.040 * | 2.15 ± 0.13 | −0.037 (−0.08; 0.07) |
0.095 * | −0.019 (−0.05; 0.09) |
0.578 |
| Log (TG/HDL) | ||||||||
| Global | 0.30 ± 0.23 | −0.033 ‡ (−0.06; −0.001) |
0.046 * | 0.31 ± 0.23 | −0.023 (−0.07; 0.02) |
0.309 * | −0.020 (−0.07; 0.04) |
0.640 |
| ≤0.24 | 0.12 ± 0.11 | −0.010 (−0.05; 0.03) |
0.613 * | 0.14 ± 0.12 | 0.009 (−0.06; 0.08) |
0.789 * | −0.020 (−0.10; 0.06) |
0.610 |
| ≤0.24 | 0.47 ± 0.17 | −0.055 ‡ (−0.11; −0.003) |
0.038 * | 0.49 ± 0.17 | −0.055 (−0.12; 0.006) |
0.073 * | −0.004 (−0.08; 0.07) |
0.909 |
ABG, aged black garlic; change, change from baseline; w, weeks; LDL, low-density lipoproteins; d, directly measured; fried, calculated by Friedewald formula; HDL, high-density lipoproteins; TGs, triglycerides. Data are expressed as the mean ± standard deviation or the mean (95% Confidence Interval, CI). Intra-treatment comparison by general linear model. P for: * quadratic trend; † linear trend; ‡ p < 0.05 vs. the baseline. Intertreatment comparisons by ANCOVA model adjusted by age, sex, and order.