Extended Data Fig. 2 |. Immunophenotyping of Ddr1-WT and Ddr1-KO tumours.

(a–d) TIL number normalized by E0771 Ddr1-WT/KO tumour weight/gram. Cell number of CD44^hi CD62L^lo CD8⁺ (a) and CD44^hi CD62L^lo CD4⁺ (b) IFNγ⁺ CD8⁺ (c) and IFNγ⁺ CD4⁺ (d) T cells. WT/KO: n = 5 tumours/group. (e–p) TIL numbers normalized by tumour weight of M-Wnt (n = 4 tumours/group, e-j) and AT-3 tumours (n = 5 tumours/group, k–p). (q–t) Percentages of T cells from E0771 Ddr1-WT and KO tumours (n = 5 tumours/group) positive for Ki67 (CD4⁺ in q and CD8⁺ in r), IFNγ (CD8⁺ in s) or GZMB (CD8⁺ in t). n.s. not significant. Values represent mean ± SEM. p value as indicated, two-tailed Student’s t-test.