Table A2.
Screening of the inhibitory effects of tested plant extracts (20 ppm) on URAT1 function.
| Descriptions in This Study | % * | Descriptions in This Study | % * | Descriptions in This Study | % * |
|---|---|---|---|---|---|
| Abelmoschus esculentus (beniokura) | 57.3 | Citrus natsudaidai (peel) | 74.5 | Matricaria recutita | 126.1 |
| Agaricus bisporus | 38.1 | Citrus paradisi (peel) | 92.4 | Matteuccia struthiopteris (young) | 116.6 |
| Allium cepa | 32.9 | Citrus reticulata (peel) | 50.2 | Mesembryanthemum crystallinum | 97.4 |
| Allium oschaninii | 59.5 | Citrus sinensis (blood orange, peel) | 65.2 | Momordica charantia (coat) | 97.8 |
| Allium sativum | 92.1 | Citrus sinensis (navel) | 81.4 | Musa spp. (peel) | 62.2 |
| Allium sativum (sprout) | 117.9 | Citrus sphaerocarpa (peel) | 119.1 | Musa spp. (peel, Ecuador) | 94.8 |
| Allium tuberosum | 77.7 | Citrus sudachi (peel) | 59.3 | Nasturtium officinale | 107.7 |
| Ananas comosus (coat) | 108.1 | Citrus tangelo (peel) | 34.7 | Nelumbo nucifera | 41.4 |
| Apium graveolens | 68.7 | Cocos nucifera (young) | 100.2 | Ocimum basilicum | 100.0 |
| Apium graveolens (salad celery) | 35.8 | Colocasia esculenta | 58.5 | Ocimum basilicum (purple) | 79.4 |
| Arachis hypogaea (beans) | 38.0 | Coriandrum sativum | 130.2 | Oryza sativa (black) | 67.8 |
| Arachis hypogaea (shell) | 24.3 | Coriandrum sativum (leaves) | 20.8 | Perilla frutescens | 81.6 |
| Aralia cordata | 43.9 | Cucumis melo (coat) | 67.3 | Persea americana (coat) | 106.7 |
| Aralia elata (sprout) | 86.4 | Cucurbita (meat) | 91.5 | Persea americana (seed) | 63.8 |
| Arctium lappa | 59.9 | Cucurbita (peel) | 66.5 | Petasites japonicus | 64.3 |
| Arctium lappa (burdock tea) | 97.4 | Cucurbita pepo (yellow, peel) | 37.8 | Petroselinum crispum (leaves) | 75.7 |
| Aspalathus linearis | 29.0 | Curcuma longa | 83.7 | Phaseolus vulgaris | 132.6 |
| Asparagus officinalis (grass roots) | 48.1 | Cyperus esculentus (powder) | 99.2 | Phaseolus vulgaris (Moroccan kidney beans) | 140.3 |
| Asparagus spp. | 77.0 | Daucus carota | 55.1 | Pholiota microspora | 55.4 |
| Auricularia auricula-judae | 31.4 | Daucus carota (purple carrot) | 52.0 | Phyllostachys pubescens (young, dried) | 47.4 |
| Barley (Hordeum vulgare) Miso | 105.5 | Dioscorea japonica | 44.8 | Pisum sativum | 62.2 |
| Basella alba | 63.5 | Diospyros kaki (shibugaki, meat) | 112.0 | Pisum sativum (shelled) | 107.8 |
| Benincasa hispida (coat, placenta, seed) | 50.3 | Diospyros kaki (shibugaki, peel) | 51.7 | Pisum sativum (shuck-edible) | 50.2 |
| Benincasa hispida (meat) | 25.2 | Eriobotrya japonica (peel) | 109.7 | Pisum sativum (young leaves) | 49.3 |
| Brassica chinensis | 93.8 | Eutrema japonicum | 73.7 | Pleurotus cornucopiae | 90.7 |
| Brassica oleracea (broccoli, anthotaxy) | 22.7 | Eutrema japonicum (stem) | 102.2 | Pleurotus eryngii | 49.9 |
| Brassica oleracea (broccoli, sprout) | 61.4 | Fagopyrum tataricum | 36.5 | Pleurotus ostreatus | 73.1 |
| Brassica oleracea (broccoli, stem) | 68.5 | Ficus carica | 79.1 | Prunus domestica (extract) | 84.4 |
| Brassica oleracea (kohlrabi, peel) | 73.4 | Flammulina velutipes | 39.7 | Prunus domestica (meat) | 96.3 |
| Brassica oleracea (red cabbage, sprout) | 106.2 | Fortunella (peel) | 62.5 | Prunus tomentosa (peel) | 49.5 |
| Brassica oleracea (romanesco broccoli, stem) | 109.8 | Fragaria ananassa | 52.0 | Psidium guajava (Chinese) | 73.4 |
| Brassica oleracea (soft kale) | 94.4 | Ginkgo biloba (seed) | 40.2 | Psidium guajava (Japanese) | 52.5 |
| Brassica oleracea (stick senor) | 51.2 | Glebionis coronaria | 17.9 | Psophocarpus tetragonolobus | 90.7 |
| Brassica oleracea (wild cabbage, flower) | 60.0 | Glycine max | 66.4 | Pteridium aquilinum | 192.2 |
| Brassica rapa (ayameyuki-kabu) | 108.2 | Glycine max (hidenmame) | 104.0 | Pyrus communis (peel) | 58.8 |
| Brassica rapa (ayameyuki-kabu, meat) | 85.2 | Glycine max (immature) | 64.6 | Raphanus sativus (leaves) | 70.8 |
| Brassica rapa (nabana) | 86.1 | Glycine max (immature, shuck) | 96.1 | Raphanus sativus (meat) | 64.7 |
| Brassica rapa (nabana, flower) | 64.2 | Glycine max × Bacillus subtilis | 60.6 | Raphanus sativus (radish sprout) | 79.6 |
| Brassica rapa (red) | 52.6 | Grifola frondosa | 69.5 | Rice (Oryza sativa) Miso | 58.6 |
| Brassica rapa (santo-sai) | 72.2 | Hibiscus rosa-sinensis | 97.5 | Rosmarinus officinalis (raw) | 13.6 |
| Capsicum annuum (redpepper) | 83.0 | Hosta sieboldiana | 45.2 | Sechium edule (meat) | 130.0 |
| Capsicum annuum (sweet pepper) | 107.8 | Houttuynia cordata | 84.0 | Sechium edule (peel, placenta) | 52.0 |
| Capsicum annuum (red) | 80.3 | Humulus lupulus (cone) | 78.9 | Sesamum indicum | 158.6 |
| Capsicum annuum (shishitou) | 73.0 | Hylocereus undatus (peel) | 120.0 | Siranuhi, (Citrus unshiu × C. sinensis) × C. reticulata (peel) | 52.7 |
| Capsicum annuum (yellow) | 81.4 | Hypsizygus marmoreus | 58.1 | Smallanthus sonchifolius | 35.4 |
| Capsicum frutescens | 58.8 | Ilex paraguariensis (roasted) | 69.1 | Smallanthus sonchifolius (meat) | 74.3 |
| Carica papaya (immature, meat) | 78.5 | Illicium verum | 24.6 | Smallanthus sonchifolius (peel) | 110.5 |
| Carica papaya (immature, peel, placenta, seed) | 94.3 | Ipomoea aquatica | 75.5 | Solanum melongena (peel) | 133.8 |
| Caulerpa lentillifera | 65.5 | Jasminum sambac | 66.5 | Vitis labruscana (peel) | 150.9 |
| Citrus aurantiifolia (peel) | 185.5 | Lactuca sativa | 91.6 | Zanthoxylum bungeanum | 57.2 |
| Citrus depressa (peel) | 38.9 | Laminaria longissima (tororomekonbu) | 112.2 | Zea mays (baby corn) | 65.3 |
| Citrus junos (peel) | 61.6 | Laurus nobilis (leaves) | 33.6 | Zea mays (kiritani) | 78.1 |
| Citrus maxima (peel) | 64.7 | Lentinula edodes | 62.8 | Zingiber mioga | 28.0 |
| Citrus maxima (placenta) | 68.9 | Lycopersicum esculentum (yellow) | 60.6 | Zingiber officinale | 57.3 |
*, Data for URAT1-mediated urate transport are expressed as % of the vehicle control (1% dimethyl sulfoxide) (n = 1, each sample). Results for the top 40 samples are shown in Figure 1.