1. Introduction	2
2. Thiamine—Vitamin B1	2
2.1. Introduction and Properties	2
2.2. Sources of Thiamine	3
2.3. Pharmacokinetics of Thiamine	7
2.4. Physiological Function of Thiamine	9
2.5. Thiamine Deficiency	10
2.6. Pharmacological Use of Thiamine	12
2.7. Toxicity of Thiamine	17
2.8. Drug-Vitamin Interactions Associated with Thiamine Deficiency	17
3. Riboflavin—Vitamin B2	17
3.1. Introduction and Properties	17
3.2. Sources of Riboflavin	17
3.3. Pharmacokinetics of Riboflavin	20
3.4. Physiological Functions of Riboflavin	23
3.5. Riboflavin Deficiency	24
3.6. Analytical Determination	25
3.7. Pharmacological Use of Riboflavin	26
3.8. Toxicity of Riboflavin	26
3.9. Drug Interactions Affecting Pharmacokinetics and Interfering with Physiological Function of Riboflavin	26
4. Niacin—Vitamin B3	27
4.1. Introduction and Properties	27
4.2. Sources of Niacin	27
4.3. Pharmacokinetics of Niacin	31
4.4. Physiological Functions of Niacin	33
4.5. Niacin Deficiency	38
4.6. Pharmacological Use of Niacin	38
4.7. Toxicity of Niacin	44
5. Pantothenic Acid—Vitamin B5	45
5.1. Introduction and Properties	45
5.2. Sources of Pantothenic Acid	45
5.3. Physiological Function of Pantothenic Acid	48
5.4. Pharmacokinetics of Pantothenic Acid	49
5.5. Pantothenic Acid Deficiency	53
5.6. Pharmacological Use of Pantothenic Acid	55
6. Conclusions	58
References	59