Table 1.
Analyses of blood chemistry during probiotic intervention at week 6.
| Week 6 | C | CH | AP-32(L) | bv-77(L) | CP-9(L) | MIX(L) | AP-32(H) | bv-77(H) | CP-9(H) | MIX(H) |
|---|---|---|---|---|---|---|---|---|---|---|
| Glucose (mg/dL) |
102.4 ± 4.16 |
109.5 ± 6.35 |
100.8 ± 9.65 |
111.4 ± 5.13 |
116.4 ± 1.67 |
113.6 ± 7.86 |
109.2 ± 5.72 |
116.4 ± 6.02 |
115.6 ± 4.93 |
106.8 ± 4.15 |
| Cholesterol (mg/dL) |
80.50 ± 8.46 |
85.67 ± 12.52 |
71.00 ± 24.49 |
70.50 ± 18.28 |
89.33 ± 15.64 |
85.50 ± 19.04 |
73.00 ± 8.27 |
63.50 * ± 12.14 |
77.33 ± 13.16 |
71.33 ± 9.69 |
| Triacylglycerol (mg/dL) |
99.50 ± 9.05 |
122.50 # ± 18.36 |
99.00 ± 25.97 |
91.83 ± 37.72 |
101.50 ± 32.38 |
105.80 ± 22.29 |
96.00 * ± 17.10 |
89.67 ± 32.16 |
91.17 ** ± 15.52 |
80.67 ** ± 19.34 |
| LDL (mg/dL) |
6.63 ± 0.75 |
8.52 # ± 0.61 |
7.90 ± 0.67 |
7.55 ± 1.30 |
7.30 ± 1.22 |
7.22 * ± 1.10 |
6.90 * ± 1.19 |
7.72 ± 0.32 |
6.00 *** ± 0.18 |
6.42 *** ± 0.49 |
| HDL (mg/dL) |
25.28 ± 2.35 |
15.82 ## ± 2.55 |
19.53 ± 5.32 |
21.33 * ± 4.77 |
21.75 * ± 4.97 |
23.63 ** ± 4.50 |
21.63 ** ± 3.41 |
22.83 ** ± 4.77 |
22.00 ** ± 2.26 |
20.48 * ± 3.42 |
| AST (U/L) |
103.83 ± 16.64 |
142.33 # ± 29.51 |
112.33 * ± 12.32 |
128.40 * ± 15.01 |
110.50 * ± 10.99 |
110.00 ** ± 5.01 |
107.67 ** ± 7.80 |
116.33 ** ± 4.27 |
109.80 ** ± 7.98 |
99.83 ** ± 13.36 |
| ALT (U/L) |
29.83 ± 5.56 |
40.83 ## ± 4.17 |
29.00 ** ± 6.10 |
22.00 ** ± 3.58 |
29.00 *** ± 6.99 |
25.67 *** ± 1.86 |
30.17 *** ± 2.04 |
21.17 *** ± 5.60 |
24.40 *** ± 3.65 |
25.00 *** ± 3.74 |
| Uric acid (mg/dL) |
1.10 ± 0.24 |
2.08 ### ± 0.21 |
1.52 ** ± 0.26 |
1.62 * ± 0.30 |
1.67 ** ± 0.10 |
1.55 * ± 0.30 |
1.35 *** ± 0.27 |
1.60 ** ± 0.30 |
1.80 * ± 0.23 |
1.55 ** ± 0.32 |
| Creatinine (mg/dL) |
0.25 ± 0.03 |
0.31 # ± 0.04 |
0.26 ± 0.05 |
0.30 ± 0.07 |
0.32 ± 0.03 |
0.25 ** ± 0.02 |
0.25 * ± 0.03 |
0.24 ** ± 0.03 |
0.27 ± 0.02 |
0.26 ± 0.03 |
Data are presented as the mean ± S.D. of six animals in each group. Statistical analysis was performed by using a one-way ANOVA. Statistical difference was compared between the C and CH groups (# p < 0.05, ## p < 0.01, and ### p < 0.001) or the CH and a probiotics-treated group (* p < 0.05, ** p < 0.01, and *** p < 0.001). C: control; CH: symptom control; MIX: probiotic mixture of AP-32, bv-77, and CP-9; L = 5 × 109 CFU/kg/day; H = 2.5 × 1010 CFU/kg/day; LDL: low-density lipoprotein; HDL: high-density lipoprotein; ALT: alanine aminotransferase, AST: aspartate Transaminase.