Skip to main content
. 2022 Jan 28;15(3):1041. doi: 10.3390/ma15031041

Table 2.

Examples for non-protein/peptide-based chitin/chitosan aerogel matrices, reporting good biocompatibility after in vitro tests and high water absorption capacity.

Aerogels Crosslinked/Blended with Additives Observed in Biomedicine Application
Chitosan Crosslinked with diatom-biosilica by in situ polymerization of dopamine (Michael-type cycloaddition) [137] Improved hemostatic performance.
No additives [143] Improved hemostatic performance
Blended with alginate producing polyelectrolyte complex [144] Efficient antibacterial activity (Staphylococcus aureus and Klebsiella pneumoniae) and effective wound closure
Crosslinked with itaconic acid using epichlorohydrin [145] Efficient antibacterial activity (Corynebacterium glutamicum and Escherichia coli)
Vancomycin, drug-loaded chitosan aerogel [97] Efficient antibacterial activity (Staphylococcus aureus) and drug release kinetics
Cellulose nanofibers dry-crosslinked in the chitosan matrix [146] Shape recoverable foam material under wet conditions showing improved hemostatic performance
Chitin No additives, electrophoretic deposition of chitin nanoparticles [138] Accelerate wound healing and reduce scar area in comparison with cryogels