Table 1.
Effects of Atractylodes macrocephala and Amomum villosum extracts (3:1) on plasma biochemical levels in high-fat diet-induced obesity in mice.
| Indexes | ND | HFD | HFD | |||
|---|---|---|---|---|---|---|
| AME:AVE (3:1) 37.5 | AME:AVE (3:1) 75 | AME:AVE (3:1) 150 | G 150 | |||
| Glucose (mg/dL) | 251.0 ± 15.1 | 374.5 ± 13.9 ### | 305.9 ± 9.8 ** | 325.3 ± 2.8 ** | 268.6 ± 6.0 *** | 301.8 ± 8.7 ** |
| T-CHO (mg/dL) | 97.5 ± 3.7 | 205.5 ± 19.5 ### | 186.0 ± 5.1 | 160.2 ± 3.1 * | 159.5 ± 4.0 | 165.5 ± 4.9 |
| TG (mg/dL) | 73.0 ± 2.6 | 98.3 ± 5.3 ## | 106.3 ± 3.2 | 92.5 ± 3.1 | 85.6 ± 4.4 | 83.5 ± 2.0 * |
| LDL-c (mg/dL) | 9.4 ± 0.2 | 37.7 ± 7.0 ## | 32.7 ± 0.8 | 29.3 ± 0.9 | 31.5 ± 1.3 | 31.9 ± 1.3 |
| HDL-c/LDL-c | 11.3 ± 0.5 | 4.7 ± 0.4 ## | 4.9 ± 0.1 | 5.3 ± 0.2 | 4.9 ± 0.3 | 4.8 ± 0.3 |
| ALT (U/L) | 29.3 ± 3.9 | 50.6 ± 6.9 ## | 40.6 ± 4.5 | 32.6 ± 1.4 * | 32.7 ± 2.6 * | 29.8 ± 0.9 * |
| AST (U/L) | 129.4 ± 8.6 | 185.9 ± 20.2 # | 144.6 ± 9.3 | 140.2 ± 3.6 * | 125.1 ± 8.5 * | 134.7± 2.9 * |
| Leptin (ng/mL) | 1.5 ± 0.1 | 48.8 ± 9.1 ### | 35.4 ± 3.1 | 26.0 ± 1.4 * | 26.7 ± 6.7 | 33.6 ± 3.7 |
| Adiponectin (ng/mL) | 14.2 ± 1.0 | 13.9 ± 0.5 | 14.1 ± 0.6 | 14.4 ± 1.1 | 14.7 ± 0.3 | 12.0 ± 0.3 |
ND, normal-diet group; HFD, high-fat diet group. # p < 0.05, ## p < 0.01, and ### p < 0.001 vs. ND group. * p < 0.05, ** p < 0.01, and *** p < 0.001 vs. HFD group.