Table 3.

High Bleeding Risk Patients

Bleeding within last 30 d needing acute care setting

History of inherited or acquired bleeding disorder

Recent ischemic stroke

History of intracranial hemorrhage

Presence of epidural or spinal catheter

Intracranial malignancy

History of bleeding diathesis (ie, hemophilia)

Recent GI bleeding (within 3 mo)

Thrombolysis in previous 7 d

Recent major surgery (within 14 d)

Uncontrolled hypertension (sBP > 200 mm Hg or dBP > 120 mm Hg)

Baseline INR > 2.0 or aPTT > 50 s

Hemoglobin < 8 g/dL

Platelet count < 50 × 109/L

Dual antiplatelet agents

Bleeding risk should be individualized and discussed on case-by-case basis. aPTT = activated partial thromboplastin time; dBP = diastolic BP; INR = international normalized ratio; sBP = systolic BP.