Table 2.
Detailed neutralization assay results in both the groups.
| 2A. Comparison of chemiluminescence assay OD S/Co with neutralization inhibition percentage among two groups | |||||
|---|---|---|---|---|---|
| Chemiluminescence assay (CLIA) |
Total n = 90 |
CCP donors n = 43 |
WB donors n = 47 |
P-value | |
| CLIA OD S/Co 6-12 (n = 33) |
(n = 28) |
(n = 5) |
|||
| CLIA OD mean (range) | 7.4 (6.1–11.8) | 7.53 (6.1–11.8) | 6.68 (6.1–7.3) | 0.157 | |
| CLIA OD S/Co 6-12 (n = 33) | Inhibition mean (range) | 76.16 (41.1–94.6) | 76.35 (41.1–94.6) | 75.1 (68.8–82.8) | |
| CLIA OD S/Co ≥ 12 (n = 57) | (n = 15) | (n = 42) | |||
|---|---|---|---|---|---|
| CLIA OD S/Co ≥ 12 (n = 57) | CLIA OD mean (range) | 24.37 (12.1–42) | 29.09 (12.1–42) | 22.69 (12.1–39.9) | 0.153 |
| Inhibition % mean (range) | 76.38 (21.1–95.4) | 79.37 (21.1–95.4) | 75.31 (44.13–94.09) | ||
| 2B. Demographic parameters and Inhibition percentage among two groups | ||||
|---|---|---|---|---|
| Demographic parameters | Number; mean inhibition % (range) |
P-value | ||
| Total n = 90 | CCP donors n = 43 | WB donors n = 47 | ||
| Age groups | 0.199 | |||
| 18–29 years | 34; 76 (45.3–94.09) | 8; 77.5 (45.3–92.9) | 26; 75.8 (47.8–94.09) | |
| 30–45 years | 52; 76.6 (21.1–95.4) | 33; 78.2 (21.1–95.4) | 19; 73.9 (44.1–89.8) | |
| 46–60 years | 4; 73.4 (45.6–89.1) | 2; 65.6 (45.6–85.7) | 2; 81.2 (73.3–89.1) | |
| Gender | – | |||
| Male | 89; 76.4 (21.1–95.4) | 42; 77.7 (21.1–95.4) | 47; 75.2 (44.1–94.0) | |
| Female | 1; 64.7 (64.7) | 1; 64.7 (64.7) | 0; () | |
| Blood groups | 0.213 | |||
| Group A | 19; 77.7 (58.4–94.3) | 10; 82.3 (64.7–94.3) | 9; 72.5 (58.4–82.8) | |
| Group AB | 11; 70.6 (44.1–93.3) | 2; 80.4 (75–85) | 9; 68.4 (44.1–93.3) | |
| Group B | 19; 74.5 (21.1–95.4) | 10; 72.9 (21.1–95.4) | 9; 76.3 (50.2–90.2) | |
| Group O | 41; 77.9 (45.3–94.6) | 21; 76.8 (45.3–94.6) | 20; 79.1 (48.6–94.0) | |
| Donation status | 0.157 | |||
| First time donor | 15; 75.7 (50.25–94.6) | 5; 83.4 (64.7–94.6) | 10; 71.8 (50.2–93.4) | |
| Repeat donation | 75; 76.4 (21.1–95.4) | 38; 76.6 (21.1–95.4) | 37; 76.2 (44.1–94.9) | |
| Type of donation | – | |||
| Voluntary donor | 63; 76.6 (21.1–95.4) | 43; 77.4 (21.1–95.4) | 20; 75.0 (44.1–93.4) | |
| Replacement donor | 27; 75.4 (47.7–94) | 0; () | 27; 75.4 (47.7–94) | |