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. 2022 Jan 18;27(3):584. doi: 10.3390/molecules27030584

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Integrated network of functional interactions between metabolites (represented by their KEGG C-codes) and genes (represented by their abbreviation names) whose levels were affected in rare minnow by MP exposure. Metabolites and genes are connected if they share at least one common KEGG pathway. Increased or decreased metabolite or mRNA abundances (genes) in MP-exposed samples are indicated by red and blue symbols, respectively. Standard names of some relevant metabolites are shown in green.