Table 1.

The effect of BPF (10 mg/Kg daily; n = 10; Group 3) or RYR (3 and 1 mg/Kg daily; n = 10 for each group; Groups 4 and 5, respectively) on serum T-CHOL, LDL-C and HDL-C, triglycerides, malondialdehyde (MDA) paraoxonase and glutathione peroxidase in rats fed a hyperlipidemic diet. Groups 1 and 2 (n = 10 for each group represent animals receiving standard or hyperlipidemic diet, respectively. Data are expressed as mean ± SD. * p < 0.05 Control (Group 1) vs. Hyperlipidemic rats (Group 2); ^§ p < 0.05 Hyperlipidemic (Group 2) vs. BPF, RYR 3 and 1 mg (Groups 3–5). Abbreviations. BPF: Bergamot Poliphenolic Fraction; RYR: Red yeast rice; T-CHOL: Total Cholesterol; LDL-C: Low density lipoprotein cholesterol; HDL-C: High density lipoprotein-cholesterol.

Study Groups	Serum T-CHOL (mg/dL)	Serum LDL-C (mg/dL)	Serum HDL-C (mg/dL)	Serum Triglycerides (mg/dL)	Serum Paraoxonase (nmol/mL/min)	Glutathione Peroxidase (U/mL)
Group 1
Standard diet (n = 10)	110 ± 12	34 ± 6	41 ± 6	145 ± 16	85 ± 6	186 ± 5
Group 2
Hyperlipidemic diet (n = 10)	196 ± 14 *	117 ± 10 *	32 ± 8 *	235 ± 18 *	132 ± 8 *	175 ± 4 *
Group 3
Hyperlipidemic diet + BPF 10 mg/Kg (n = 10)	154 ± 12 §	73 ± 8 §	46 ± 7 §	175 ± 15 §	102 ± 10 §	214 ± 4 §
Group 4
Hyperlipidemic diet + RYR (3 mg/Kg) (n = 10)	164 ± 14 §	83 ± 7 §	38 ± 5	215 ± 19	106 ± 9 §	192 ± 5
Group 5
Hyperlipidemic diet + RYR (1 mg/Kg) (n = 10)	176 ± 14 §	94 ± 11 §	36 ± 6	222 ± 16	116 ± 5 §	194 ± 6