Table 2. Univariate and Multivariate Logistic Regression Models for Graft-Versus-Host Disease .
|
Variable |
Univariate | Multivariate | ||
| Odds Ratio (80% CI) | p | Adjusted Odds Ratio (90% CI) | p | |
| Recipient Age | 0.99 (0.97-1.008) | 0.465 | ||
| Donor Age | 1.01 (0.99-1.04) | 0.252 | ||
| DP1 Gender | 0.173* | 0.009** | ||
| Female-Female | 0.80 (0.43-1.50) | 0.162 | 0.11 (0.01-0.64) | 0.033 |
| Female-Male | 1.58 (0.93-2.69) | 0.367 | 0.47 (0.11-1.83) | 0.556 |
| Male-Female | 1.92 (1.17-3.17) | 0.069 | 3.49 (1.16-11.50) | 0.001 |
| Male-Male (RL1) | - | - | - | - |
| Recipient BMI | 0.170* | 0.041** | ||
| Below 18.5 | 0.42 (0.21-0.85) | 0.048 | 0.04 (0.007-0.27) | 0.013 |
| Between 18.5-24.9 | 1.19 (0.68-2.09) | 0.088 | 0.30 (0.08-1.09) | 0.566 |
| Between 25-29.9 | 0.83 (0.45-1.51) | 0.91 | 0.25 (0.06-0.94) | 0.908 |
| Above 30 (RL1) | - | - | - | - |
| Diagnosed disease | 0.912 | |||
| NHL | 1.71 (0.45-6.41) | 0.444 | ||
| HD | 1.14 (0.29-4.49) | 0.984 | ||
| AML | 1.21 (0.38-3.79) | 0.866 | ||
| ALL | 1.51 (0.47-4.87) | 0.420 | ||
| Aplastic Anemia | 0.66 (0.14-3.06) | 0.434 | ||
| Other (RL1) | - | - | ||
| Recipient CMV Ag | 0.033* | 0.081** | ||
| Negative | 0.26 (0.11-0.60) | 0.033 | 0.24 (0.06-0.93) | 0.081 |
| Positive (RL1) | - | - | - | - |
| Donor-recipient relationship | 0.109* | 0.029** | ||
| Related | 0.55 (0.33-0.89) | 0.109 | 0.08 (0.01-0.60) | 0.029 |
| Sibling (RL1) | - | - | - | - |
| HLA | 0.393 | |||
| Match | 2.60 (0.61-11.07) | 0.393 | ||
| Mismatch (RL1) | - | - | ||
| Complete Remission | 0.971 | |||
| CR2 | 1.01 (0.53-1.91) | 0.844 | ||
| CR3 | 0.76 (0.15-3.73) | 0.816 | ||
| CR1 (RL1) | - | - | ||
| Partial Remission | 0.755 | |||
| PR2 | 3.75 (0.74-25.58) | 0.402 | ||
| PR3 | 3 (0.28-36.33) | 0.733 | ||
| PR4 | 1.5 (0.16-14.26) | 0.770 | ||
| PR1 (RL1) | - | - | ||
| ATG | 0.664 | |||
| No | 1.22 (0.67-2.22) | 0.664 | ||
| Yes (RL1) | - | - | ||
| Conditioning Regimen | 0.644 | |||
| Bu/Cy | 1.50 (0.71-3.13) | 0.352 | ||
| Bu/Fu | 1.13 (0.56-2.38) | 0.866 | ||
| Bu/Fu/ATG | 1.45 (0.34-2.01) | 0.558 | ||
| RIC (RL1) | - | - | ||
| Prophylaxis Regimen | 0.955 | |||
| CSA+MTX | 0.97 (0.51-1.82) | 0.955 | ||
| CSA+MTX+ATG (RL1) | ||||
| Recipient Blood Group | 0.170* | |||
| A | 2.1 (1.29-3.39) | 0.048 | ||
| B | 1.55 (0.9-2.65) | 0.551 | ||
| AB | 0.91 (0.46-1.80) | 0.322 | ||
| O (RL1) | - | - | ||
| Compatibility Blood Group | 0.588 | |||
| Incompatible | 1.17 (0.79-1.73) | 0.588 | ||
| Compatible (RL1) | - | - | ||
1. Reference Level
* Significant at 0.2
** Significant at 0.1