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. Author manuscript; available in PMC: 2023 Feb 1.
Published in final edited form as: J Card Fail. 2021 Dec 23;28(2):202–211. doi: 10.1016/j.cardfail.2021.10.019

Table 4.

Association of arterial stiffness and load with abnormal PCWP/CO slope in men and women with HFpEF

Women Men
Arterial Stiffness OR (95% CI) p-value OR (95% CI) p-value P int
AP, mmHgǂ 3.16 (1.34–7.42) 0.008 2.07 (0.95–5.49) 0.15 0.27
AIx, %ǂ 2.11 (1.03–4.36) 0.04 1.93 (0.78–4.77) 0.16 0.21
AoPP, mmHgǂ 2.96 (1.25–7.00) 0.01 1.86 (0.78–4.41) 0.16 0.49
Ischemic Predisposition
SEVR, mmHgǂ 0.41 (0.18–0.93) 0.03 0.66 (0.33–1.32) 0.24 0.96
Arterial Load
SVRI, dynes·sec/cm5/m2 1.58 (0.85–2.95) 0.15 1.13 (0.62–2.07 0.68 0.64
Eal, mmHg·m2/mL 1.52 (0.77–3.00) 0.22 0.92 (0.51–1.68) 0.79 0.27
TACI, mL/mmHg·m2 0.36 (0.16–0.81) 0.01 0.58 (0.26–1.33) 0.20 0.27
PPA 0.61 (0.35–1.06) 0.08 0.59 (0.30–1.15) 0.12 0.23

OR: odds ratio per 1-SD increase in standardized and log-transformed continuous variable. Model adjusts for age. Further adjusted for heart rate where noted by ǂ. Abbreviations: AP = augmentation pressure, AIx = augmentation index, AoPP = aortic pulse pressure, SEVR = subendocardial viability ratio, TTI = tension time index, DPTI = diastolic perfusion time index, SVRI = systemic vascular resistance index, EaI = effective arterial elastance index, TACI = total arterial compliance index, PPA = pulse pressure amplification.