Table 2.
Results of matched, fully-adjusted Cox proportional hazards model comparing the risk of incident, cause-specific mortality in gastric bypass and sleeve gastrectomy patients compared to matched non-surgical patients
| Hazard ratios comparing gastric bypass vs. matched non-surgical patients | ||||
|---|---|---|---|---|
| Hazard Ratio (95% CI) at 1 Year after Index Date | Hazard Ratio (95% CI) at 3 Years after Index Date | Hazard Ratio (95% CI) at 5 Years after Index Date | Hazard Ratio (95% CI) at 7 Years after Index Date | |
| Cardiovascular-related mortalitya | 0.46 (0.39, 0.54) | 0.18 (0.13, 0.25) | 0.27 (0.20, 0.37) | 0.76 (0.53, 1.09) |
| Cancer-related mortalitya | 0.69 (0.57, 0.82) | 0.44 (0.29, 0.64) | 0.54 (0.39, 0.76) | 0.91 (0.56, 1.48) |
| Diabetes-related mortalitya | 0.49 (0.39, 0.61) | 0.19 (0.12, 0.31) | 0.23 (0.15, 0.36) | 0.45 (0.25, 0.80) |
| Hazard ratios comparing sleeve gastrectomy vs. matched non-surgical patients | ||||
| Hazard Ratio (95% CI) at 1 Year after Index Date | Hazard Ratio (95% CI) at 3 Years after Index Date | Hazard Ratio (95% CI) at 5 Years after Index Date | Hazard Ratio (95% CI) at 7 Years after Index Date | |
| Cardiovascular-related mortalitya | 0.46 (0.30, 0.71) | 0.33 (0.19, 0.58) | 0.57 (0.19, 1.71) | NA |
| Cancer-related mortalitya | 0.42 (0.21, 0.86) | 0.26 (0.11, 0.59) | 0.39 (0.06, 2.29) | NA |
| Diabetes-related mortalitya | 0.23 (0.10, 0.53) | 0.15 (0.04, 0.53) | 0.69 (0.15, 3.24) | NA |
For cause-specific mortality analyses, the cause of death could be listed as “primary” or “contributing”. Due to small sample sizes, estimates for sleeve gastrectomy could not be reliably calculated 7 years after the index date.