Table 2.
Rates of pCR and near-pCR between patients with and without PET response by induction chemotherapy group and between groups
| Characteristic | FOLFOX (n=70) | CP (n=239) | P (FOLFOX vs. CP) | No Induction (n=142) | P (FOLFOX vs. No Induction) |
|---|---|---|---|---|---|
| PET response | 50 (71) | 154 (64) | 0.32 | N/A | |
| pCR | |||||
| All patients | 23 (33) | 39 (16) | 0.004 | 31 (22) | 0.10 |
| PET response | 19/50 (38) | 31/154 (20) | 0.014 | 0.038 | |
| PET nonresponse | 4/20 (20) | 8/85 (9) | 0.24 | >0.99 | |
| P (within each induction group, PET response vs. nonresponse) | 0.17 | 0.043 | N/A | ||
| Near-pCR | |||||
| All patients | 40 (57) | 80 (33) | <0.001 | 59 (42) | 0.040 |
| PET response | 30/50 (60) | 60/154 (39) | 0.013 | 0.032 | |
| PET nonresponse | 10/20 (50) | 20/85 (24) | 0.027 | 0.48 | |
| P (within each induction group, PET response vs. nonresponse) | 0.59 | 0.022 | N/A |
Data are no. (%). Statistical analysis was performed using Fisher’s exact test. CP, carboplatin plus paclitaxel; N/A, not applicable; pCR, pathologic complete response; PET, positron emission tomography.