TABLE 7.

Associations between degree of liver steatosis or fibrosis and serum ferritin (ng/ml) in adults with NAFLD

Exposure	Model 1:β (95% CI), p	Model 2:β (95% CI), p	Model 3:β (95% CI), p
Severe steatosis (S3)
CAP < 302	Reference	Reference	Reference
CAP ≥ 302	9.1 (−14.1, 32.2), 0.443	−1.1 (−23.6, 21.5), 0.925	−7.3 (−29.0, 14.4), 0.508
Significant fibrosis (≥F2)
LSM < 8.0	Reference	Reference	Reference
LSM ≥ 8.0	95.4 (59.4, 131.4), <0.001	84.3 (49.3,119.4), <0.001	5.9 (−29.5, 41.2), 0.745
Advanced fibrosis (≥F3)
LSM < 9.7	Reference	Reference	Reference
LSM ≥ 9.7	74.2 (44.8, 103.7), <0.001	65.5 (36.8, 94.1), <0.001	−0.7 (−29.8, 28.4), 0.960
Cirrhosis (F4)
LSM < 13.6	Reference	Reference	Reference
LSM ≥ 13.6	147.9 (93.2,202.6), <0.001	141.6 (88.5,194.6),<0.001	38.9 (−15.2, 93.0), 0.159

Model 1: no covariates were adjusted. Model 2: age, gender, race were adjusted. Model 3: age, gender, race, BMI, diabetes, waist circumference, HDL‐cholesterol, glycohemoglobin, AST, ALT, GGT, serum albumin, serum creatinine, and uric acid were adjusted.

Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; GGT, gamma glutamyl transpeptidase; HDL, high density lipoprotein; NAFLD, non‐alcoholic fatty liver disease.