Table 1.
Characteristics of breast cancer patients vs. healthy controls
| Healthy controls (n = 86) | Breast cancer (n = 95) | p value | |
|---|---|---|---|
| Age (years) | 61 (26–88) | 64 (39–92) | 0.15* |
| BMI (Kg/m2) | 24.8 (15.6–36.9) | 23.9 (14.3–37.8) | 0.33* |
| pT | |||
| 1 | – | 76 (80%) | – |
| 2 | – | 19 (20%) | – |
| pN | |||
| 0 | – | 75 (78.9%) | – |
| 1 | – | 20 (21.1%) | – |
| Grading | |||
| 1 | – | 7 (7.4%) | – |
| 2 | – | 64 (67.4%) | – |
| 3 | – | 24 (25.2%) | – |
| Molecular subtype | |||
| Luminal A | – | 73 (76.8%) | – |
| Luminal B | – | 14 (14.7%) | – |
| Triple negative | – | 8 (8.4%) | – |
| Median plasma concentrations of EV (ng/µL) | 613.0 [IQR: 765.2] | 1779.1 [IQR: 4072.2] | < 0.0001* |
| (Range) | 30.0–6862.0 | 72.1–22,805.9 | |
*p-value from Mann–Whitney Test