Table 3.
ROCK2 Gene rs9808232 Polymorphism in Relation to Clinical Parameters in Patients with Hepatocellular Carcinoma
| AFP | >400ng/mL (n=182) | <400ng/mL (n=22) | χ2 | P value |
| AA | 37(20.3) | 3(13.6) | 1.852 | 0.396 |
| AC | 102(56.1) | 11(50.0) | ||
| CC | 43(23.6) | 8(36.4) | ||
| Imaging Classification | Lump Type (n=125) | Nodular/Diffuse Types (n=79) | χ2 | P value |
| AA | 19(15.2) | 21(26.5) | 4.476 | 0.107 |
| AC | 71(56.8) | 42(53.2) | ||
| CC | 35(28.0) | 16(20.3) | ||
| TNM Staging | I/II (n=81) | III/IV (n=123) | χ2 | P value |
| AA | 16(19.7) | 24(19.5) | 0.007 | 0.996 |
| AC | 45(55.6) | 68(55.3) | ||
| CC | 20(24.7) | 31(25.2) | ||
| Transfer Route | Intrahepatic Metastasis (n=89) | Extrahepatic Metastasis (n=115) | χ2 | P value |
| AA | 11(12.4) | 29(25.2) | 6.133 | 0.047 |
| AC | 51(57.3) | 62(53.9) | ||
| CC | 27(30.3) | 24(20.9) |
Abbreviations: OR, odds ratio; AFP, alpha-fetoprotein; TNM staging, tumor node metastasis staging.