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. 2022 Jan 31;12:658862. doi: 10.3389/fgene.2021.658862

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Copyright © 2022 Jo, Seo, Gil, Park, Han, Han, Thimmulappa, Kim and Kim.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cellular heterogeneity within the filtered induced macrophages (iMACs) analyzed by Seurat method. In total, 3,092 hESC derived iMACs (hESC-iMAC) and 3,138 hiPSC derived iMAC (hiPSC-iMAC) were analyzed via two-dimensional UMAP analysis to visualize their similarity. (A) The iMACs were grouped into 6 (hESC-iMAC) and 8 (hiPSC-iMAC) clusters. The color codes are as indicated. (B) The dendrogram showing associations among clusters. The bottom of the branch indicates the number of cells in each cluster. (C) Heatmap shows the expression of the top 10 genes of each group.