TABLE 2.
Changes in markers of mineral metabolism at baseline and after 12 weeks of treatment with calcium acetate or sevelamer carbonate
| Calcium acetate | Sevelamer carbonate | |||
|---|---|---|---|---|
| Baseline | Week 12 | Baseline | Week 12 | |
| Calcium (mg/dl) | 9.5 ± 0.11 | 9.7 ± 0.13* | 9.6 ± 0.12 | 9.5 ± 0.10 |
| Phosphate (mg/dl) | 3.7 ± 0.73 | 3.7 ± 0.17 | 3.3 ± 0.70 | 3.4 ± 0.16 |
| FGF−23 (pg/L) | 106.4 ± 23.9 | 101.1 ± 19.8 | 112.8 ± 25.9 | 96.3 ± 13.99* |
| Calcidiol (ng/ml) | 23.9 ± 3.0 | 27.5 ± 2.7 | 31.4 ± 3.1 | 28.9 ± 3.5 |
| Calcitriol (pg/ml) | 35.6 ± 3.9 | 36.8 ± 3.8 | 44.4 ± 4.1 | 38.4 ± 3.9* |
| Ca × P (mg2/dl2) | 35.8 ± 1.94 | 36.71 ± 1.94 | 32.03 ± 1.7 | 32.97 ± 1.56 |
| PTH (pg/ml) | 70.8 ± 14.1 | 51.2 ± 11.09* | 58.0 ± 5.34 | 66.2 ± 5.36 |
All data are mean ± SD. Paired comparison from baseline to week 12 change. *p < 0.05.
Abbreviations: Ca × P, calcium × phosphate; FGF‐23, fibroblast growth factor 23; PTH, parathyroid.