TABLE 3.
Changes in levels in vascular calcification markers at baseline and after 12 weeks of treatment with calcium acetate and sevelamer carbonate
| Calcium acetate | Sevelamer carbonate | |||
|---|---|---|---|---|
| Baseline | Week 12 | Baseline | Week 12 | |
| OPG (pg/ml) | 2409 ± 188 | 2437 ± 201.4 | 2813 ± 612.6 | 2817 ± 489.4 |
| SOST (pg/ml) | 234.4 ± 26.8 | 213.1 ± 27.39* | 213.1 ± 27.18 | 208.3 ± 26.08* |
| TRAcP5b (U/L) | 3.00 ± 0.21 | 2.69 ± 0.17* | 3.07 ± 0.21 | 3.05 ± 0.22 |
| AlkPO4 (IU/L) | 60.53 ± 5.23 | 56.73 ± 4.24 | 68.6 ± 5.65 | 79.6 ± 6.52 |
All data are mean ± SD, Paired comparison from baseline for each subject to week 12 change. *p < 0.05.
Abbreviations: AlkPO4, alkaline phosphate; OPG, osteoprotegerin; SOST, serum sclerostin; TRAcP5b, serum tartrate‐resistant acid phosphatase.