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. 2022 Jan 31;12:739875. doi: 10.3389/fendo.2021.739875

Table 6.

Comparison of clinical characteristics in subjects with no MetS components based on whether they were with or without hepatic steatosis.

Characteristics Controlled attenuation parameter (dB/m) p
<238 ≥238
n 212 71
Age (years) 41.2 ± 11.3 45.4 ± 13.2 0.011
Gender, male, n (%) 27 (12.7%) 15 (21.1%) 0.085
Body mass index (kg/m2) 21.5 ± 2.1 22.7 ± 2.2 0.000
Waist circumference (cm) 74.4 ± 6.0 78.3 ± 5.6 0.000
Waist-to-hip ratio 0.82 ± 0.05 0.85 ± 0.05 0.000
Neck circumference (cm) 32.5 (31.0, 33.8) 33.5 (32.0, 35.5) 0.001
Systolic pressure (mmHg) 110 (106, 120) 110 (107, 120) 0.484
Diastolic pressure (mmHg) 68 (62, 72) 69 (65, 72) 0.558
Drinking status, n (%) 39 (18.4%) 11 (15.5%) 0.720
Smoking status, n (%) 3 (1.4%) 1 (1.4%) 1.000
Dyslipidemia, n (%) 23 (10.8%) 14 (19.7%) 0.055
Controlled attenuation parameter (dB/m) 206 (189, 224) 259 (246, 280) 0.000
Liver stiffness measurement (kPa) 3.8 (3.3, 4.4) 3.7 (3.3, 4.4) 0.197
Fasting plasma glucose (mmol/L) 4.9 (4.6, 5.1) 4.9 (4.7, 5.3) 0.071
Cholesterol (mmol/L) 4.90 (4.40, 5.40) 5.00 (4.60, 5.60) 0.142
Triglyceride (mmol/L) 0.82 (0.65, 1.04) 0.94 (0.75, 1.22) 0.002
LDL-c (mmol/L) 3.26 ± 0.67 3.43 ± 0.64 0.122
HDL-c (mmol/L) 1.61 ± 0.29 1.56 ± 0.35 0.280
Alanine transaminase (U/L) 15 (12, 20) 17 (13, 22) 0.077
Aspartate transaminase (U/L) 20 (18, 23) 21 (18, 25) 0.328
Creatinine (μmol/L) 58 (53, 67) 60 (54, 72) 0.069
Estimated glomerular filtration rate (ml/min/1.73 m2) 102.3 ± 19.0 96.7 ± 16.5 0.031
Uric acid (μmol/L) 295 (251, 346) 334 (273, 381) 0.005
Adiponectin (μg/ml) 20.6 (12.2, 29.7) 10.7 (6.8, 20.3) 0.000
Fasting serum insulin (μU/ml) 4.14 (2.96, 5.74) 5.32 (3.72, 6.61) 0.018
White blood cell count (×109/L) 5.8 (5.0, 6.7) 6.3 (4.8, 7.3) 0.041
TyG 4.38 (4.25, 4.51) 4.43 (4.31, 4.59) 0.001
METS-IR 27.1 (24.8, 29.4) 28.9 (25.5, 31.4) 0.011
HOMA-IR 0.87 (0.63, 1.26) 1.09 (0.79, 1.47) 0.023

MetS, metabolic syndrome; HOMA-IR, homeostatic model assessment of insulin resistance; TyG, the product of fasting triglycerides and glucose; METS-IR, metabolic score for insulin resistance; LDL-c, low-density lipoprotein cholesterol; HDL-c, high-density lipoprotein cholesterol.