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. 2022 Jan 31;10:812271. doi: 10.3389/fcell.2022.812271

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Copyright © 2022 Sun, Jia, Zhang, Wang, Li and Fang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A)Typical images of IHC in 16 pairs of colon cancer tissues showing the protein expression of ASNS, CEBPA and CAD in colon cancer tissues and adjacent nontumor tissues. Up panel, scale bar 1000 µm; down panel, scale bar 100 µm. (B) Immunohistochemical positive cell rates of ASNs, CEBPA, and CAD in 7 colon cancer tissues and adjacent nontumor tissues in group 1. (C) Immunohistochemical positive cell rates of ASNS, CEBPA and CAD in 9 colon cancer tissues and adjacent nontumor tissues in group 2. *p < 0.05, **p < 0.01 and ***p < 0.001, analyzed using unpaired t-test. Group 1, n = 7; Group 2, n = 9.