Table 1. Trials characteristics summary.
Study | Recruitment | Number of patients | Stage | Total dose (Gy) | Fractions | Machine |
---|---|---|---|---|---|---|
Belgium (5) | 1966–1977 | 202 | I, II, III | 60 | 30 | Cobalto 60 |
LCSGS 773 (6) | 1978–1985 | 230 | II, III | 50 | 25–27.5 | Cobalto 60 + Linac |
CAMS 12 (7) | 1981–1995 | 317 | II, III | 60 | 30 | Cobalto 60 + Linac |
Lille 13 (8) | 1985–1991 | 163 | I | 45–60 | 22.5–30 | Cobalto 60 + Linac |
EORTC 08861 (12) | 1986–1990 | 106 | II, III | 56 | 28 | Linac |
MRC LU 11 (9) | 1986–1993 | 308 | II, III | 40 | 15 | Cobalto 60 + Linac |
GETCB 04CB86 (11) | 1986–1994 | 189 | I, II, III | 60 | 24–30 | Cobalto 60 + Linac |
Slovenia (10) | 1988–1992 | 74 | III | 30 | 10–12 | Cobalto 60 + Linac |
GETCB 05CB88 (11) | 1988–1994 | 539 | I, II, III | 60 | 24–30 | Cobalto 60 + Linac |
The Italy trial (12) | 1989–1997 | 104 | I | 50.4 | 28 | Linac |
The Korea trial (13) | 1989–1998 | 111 | III | 50.4–55.8 | 28–31 | NR |
Lung ART trial (3) | 2007–2018 | 501 | II, III | 54 | 27 | Linac |