Table 1.
Clinical Features in Different Genotypes
| Overall | BRAF Positive | RET Positive | BRAF & RET Negative | |||||
|---|---|---|---|---|---|---|---|---|
| 395 | 310 | 28 | 65 | |||||
| No. | % | No. | % | No. | % | No. | % | |
| Mean age, years | 44.43* | 44.74 (p=0.737)* | 36.25 (p=0.001)* | 45.89 (p=0.408)* | ||||
| <45 | 188 | 48.7 | 142 | 47.0 | 22 | 78.6 | 29 | 45.3 |
| ≥45 | 198 | 51.3 | 160 | 53.0 | 6 | 21.4 | 35 | 54.7 |
| <55 | 296 | 76.7 | 230 | 76.2 | 27 | 96.4 | 46 | 71.9 |
| ≥55 | 90 | 23.3 | 72 | 23.8 | 1 | 3.6 | 18 | 28.1 |
| Gender | p=0.608* | p=0.660* | p=0.119* | |||||
| Male | 99 | 25.1 | 83 | 26.8 | 6 | 21.4 | 11 | 16.9 |
| Female | 296 | 74.9 | 227 | 73.2 | 22 | 78.6 | 54 | 83.1 |
| Location | ||||||||
| Bilateral | 96 | 24.3 | 74 | 23.9 | 8 | 28.6 | 17 | 26.1 |
| Right side | 166 | 42.0 | 130 | 42.0 | 14 | 50 | 25 | 38.5 |
| Left side | 133 | 33.7 | 106 | 34.1 | 6 | 21.4 | 23 | 35.4 |
| T stage | p=0.776* | p=0.001* | p<0.001* | |||||
| T1 | 198 | 78.0 | 160 | 78.1 | 6 | 27.3 | 32 | 91.4 |
| T2 | 20 | 7.9 | 14 | 6.8 | 4 | 18.2 | 3 | 8.6 |
| T3 | 23 | 9.0 | 21 | 10.2 | 5 | 22.7 | 0 | 0 |
| T4 | 13 | 5.1 | 10 | 4.9 | 7 | 31.8 | 0 | 0 |
| N stage | p=0.953* | p<0.001* | p=0.127* | |||||
| N0 | 178 | 45.1 | 139 | 44.8 | 3 | 10.7 | 36 | 55.4 |
| N1a | 145 | 36.7 | 116 | 37.4 | 8 | 28.6 | 23 | 35.4 |
| N1b | 72 | 18.2 | 55 | 17.8 | 17 | 60.7 | 6 | 9.2 |
Note: *The t-test was performed to examine the mean age, proportion of women, proportion of T3 and T4 stage, and proportion of N1 stage between Overall patients and each subgroups classified by genotypes.