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. 2022 Jan 31;12:678025. doi: 10.3389/fonc.2022.678025

Table 1.

Multivariate Cox regression analysis in male TC patients.

Multivariate analysis
p-value HR (95% CI)
ASF1B
(High expression level vs. Low expression level)*
0.001 7.823 (2.266–27.013)
Age (>60 vs. ≤60) 0.928 0.943 (0.266–3.339)
Histological type
(NON PTC vs. PTC)**
0.988 0.001 (0.001–∞)
Tumor size
(T3–4 vs. T1–2)
0.552 1.481 (0.406–5.406)
Lymph node status
(N1 vs. N0&Nx)
0.447 0.637 (0.201–2.034)
Metastasis
(M1 vs. M0&Mx)
0.629 1.717 (0.192–15.361)
Pathological stage
(S3–4 vs. S1–2)
0.098 3.666 (0.787–17.072)
Extent of the primary tumor
(Single lobectomy vs. Multiple lobectomies)***
0.451 6.937 (0.449–6.038)

Tumor stage (T), lymph node metastasis stage (N), and metastasis (M) were divided into two groups according to the 8th American Joint Committee on Cancer (AJCC) editions. *Grouped according to the best cutoff points determined by the ROC curve. **PTC, Papillary thyroid carcinoma. ***In thyroid surgical practice, the thyroid is divided into three anatomical zones, the left lobe, right lobe, and thyroid isthmus.