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. 2022 Jan 31;13:825428. doi: 10.3389/fimmu.2022.825428

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Copyright © 2022 Wang, Shi, An, Li, Bai, Wu, Shen, Du, Cheng, Wu and Xu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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PEITC ameliorated the acute immune liver injury model induced by ConA in mice. (A) Chemical structure of PEITC. (B) Schematic overview of the ConA-induced acute immune liver injury model. (C) The lesions on the surface of liver tissues were photographed and recorded. (D) The liver indexes were measured. (E) The lesions on the surface of spleen tissues were photographed and recorded. (F) The spleen indexes were measured. (G) Hematoxylin and eosin (H&E) staining of liver tissue sections. Scale bar, 200 µm. Data are presented as means ± SEM (n = 10 per group). ^###p < 0.001 vs. normal group, ^*p < 0.05, ^**p < 0.01, ^***p < 0.001 vs. ConA control.