Table 1.

PICAR inclusion criteria.

Population & clinical indication	Patients with depression Any age Any symptom severity
Interventions	Antidepressant treatment
Comparators, comparisons and content	Comparators: Any, including none Key content: Guidance on stopping or reducing treatment
Attributes of eligible CPGs	Language: Available in English Year of publication: Most recent from each organisation Publishing region: English-speaking, high-income countries Version: Latest version only System of rating evidence: Any Scope: Must have primary focus on treatment of depression Recommendations: No restrictions; CPGs will be included regardless of whether they contain guidance on tapering/discontinuation treatment or not
Recommendation characteristics	Duration of treatment: No restrictions Levels of confidence: No restrictions Interventions: No restrictions Comparators: No restrictions; recommendations are not required to compare an intervention of interest with another intervention Locating recommendations: Within CPG text, tables, algorithms or decision paths

CPG, clinical practice guideline.