Table 5.
Quality appraisal of guidance on stopping and tapering antidepressants in clinical practice guidelines on depression using the AGREE II tool.
| Guideline | AGREE II domain scores (%) | ||||||
|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | 6 | Overall | |
| BAP 2 | 58 | 44 | 14 | 28 | 0 | 38 | 17 |
| RANZCP 3 | 39 | 39 | 18 | 39 | 0 | 42 | 25 |
| HSE + ICGP 42 | 31 | 25 | 0 | 8 | 0 | 0 | 8 |
| CANMAT 37 | 50 | 28 | 25 | 19 | 6 | 50 | 8 |
| WFSBP 44 | 64 | 22 | 19 | 31 | 0 | 25 | 17 |
| AAP 26 | 78 | 44 | 18 | 0 | 0 | 13 | 8 |
| SIGN + HIS 40 | 75 | 50 | 27 | 22 | 0 | 4 | 8 |
| VA/DoD 27 | 78 | 61 | 50 | 17 | 8 | 8 | 17 |
| WHO46,47 | 94 | 69 | 43 | 11 | 27 | 58 | 17 |
| American Psychiatric Association 28 | 42 | 11 | 27 | 19 | 0 | 38 | 25 |
| NZGG + MoH (NZ) 29 | 78 | 47 | 24 | 25 | 17 | 71 | 25 |
| NICE 33 | 92 | 78 | 41 | 17 | 13 | 42 | 25 |
| WFSBP 45 | 58 | 19 | 22 | 19 | 4 | 25 | 17 |
| AACAP 48 | 53 | 14 | 27 | 19 | 0 | 13 | 17 |
| NICE 1 | 83 | 83 | 43 | 33 | 21 | 54 | 33 |
| RCPSYCH 35 | 33 | 3 | 30 | 14 | 0 | 17 | 8 |
| MoH (SI) 41 | 50 | 56 | 18 | 25 | 4 | 0 | 8 |
| NCCMH 36 | 56 | 58 | 36 | 33 | 8 | 50 | 25 |
| Mean (SD) | 62 (20) | 42 (23) | 27 (12) | 21 (10) | 6 (8) | 30 (22) | 17 (8) |
AACAP, American Academy of Child and Adolescent Psychiatry; AAP, American Academy of Pediatrics; APA, American Psychological Association; BAP, British Association for Psychopharmacology; CANMAT, Canadian Network for Mood and Anxiety Treatments; HIS, Healthcare Improvement Scotland; HSE, Health Service Executive; ICGP, College of General Practitioners; MoH (Si), Ministry of Health, Singapore; NCCMH, National Collaborating Centre for Mental Health; NICE, National Institute for Health and Care Excellence; NZ, New Zealand; NZGG, New Zealand Guidelines Group; RANZCP, Royal Australian and New Zealand College of Psychiatrists; RCPSYCH, Royal College of Psychiatrists; SD, Standard deviation; SIGN, Scottish Intercollegiate Guidelines Network; VA/DoD, Department of Veteran Affairs and Department of Defense; WFSBP, World Federation of Societies of Biological Psychiatry; WHO, World Health Organization. Values represent the mean of the scores of individual researchers. Domain 1: scope and purpose; domain 2: stakeholder involvement; domain 3: rigour of development; domain 4: clarity of presentation; domain 5: applicability; domain 6: editorial independence.