Table III.
Concentrations for NOMG, OMG, NOM, 6α-Oxycodol, 6β-Oxycodol, NOC and OC after a Single Dose of OC
| Time (h) |
Creatinine (mg/mL) |
NOMG (μg/mL) |
OMG (μg/mL) |
NOM (μg/mL) |
αOCL (μg/mL) |
βOCL (μg/mL) |
NOC (μg/mL) |
OC (μg/mL) |
NOMG (μg/mg) | OMG (μg/mg) | NOM (μg/mg) | αOCL (μg/mg) | βOCL (μg/mg) | NOC (μg/mg) | OC (μg/mg) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Creatinine | Creatinine | Creatinine | Creatinine | Creatinine | Creatinine | Creatinine | |||||||||
| 0 | 1.5 | ||||||||||||||
| 0.5 | 0.95 | 0.058 | 0.091 | 0.06 | 0.096 | ||||||||||
| 1 | 0.34 | 0.18 | 0.045 | 0.024 | 0.031 | 0.46 | 0.85 | 0.53 | 0.13 | 0.071 | 0.091 | 1.4 | 2.5 | ||
| 1.5 | 0.31 | 0.33 | 0.055 | 0.030 | 0.038 | 0.51 | 0.98 | 1.1 | 0.18 | 0.097 | 0.12 | 1.6 | 3.2 | ||
| 2 | 0.26 | 0.39 | 0.050 | 0.024 | 0.034 | 0.47 | 0.69 | 1.5 | 0.19 | 0.092 | 0.13 | 1.8 | 2.7 | ||
| 3 | 0.25 | 0.39 | 0.057 | 0.023 | 0.041 | 0.50 | 0.61 | 1.6 | 0.23 | 0.092 | 0.16 | 2.0 | 2.4 | ||
| 4 | 0.27 | 0.32 | 0.054 | 0.020 | 0.041 | 0.46 | 0.47 | 1.2 | 0.20 | 0.074 | 0.15 | 1.7 | 1.7 | ||
| 5 | 0.83 | 0.097 | 0.89 | 0.14 | 0.053 | 0.11 | 1.4 | 1.1 | 0.12 | 1.1 | 0.17 | 0.064 | 0.13 | 1.7 | 1.3 |
| 6 | 0.65 | 0.059 | 0.57 | 0.10 | 0.030 | 0.062 | 0.96 | 0.57 | 0.090 | 0.88 | 0.15 | 0.046 | 0.10 | 1.5 | 0.88 |
| 8 | 0.26 | 0.20 | 0.050 | 0.029 | 0.34 | 0.19 | 0.77 | 0.19 | 0.11 | 1.3 | 0.73 | ||||
| 9 | 0.33 | 0.18 | 0.055 | 0.038 | 0.35 | 0.18 | 0.55 | 0.17 | 0.12 | 1.1 | 0.55 | ||||
| 10 | 0.45 | 0.23 | 0.064 | 0.016 | 0.040 | 0.49 | 0.21 | 0.51 | 0.14 | 0.036 | 0.089 | 1.1 | 0.47 | ||
| 12 | 0.28 | 0.17 | 0.036 | 0.018 | 0.25 | 0.059 | 0.61 | 0.13 | 0.064 | 0.89 | 0.21 | ||||
| 14 | 1.3 | 0.11 | 0.91 | 0.075 | 0.023 | 0.06 | 0.95 | 0.20 | 0.085 | 0.70 | 0.058 | 0.018 | 0.046 | 0.73 | 0.15 |
| 24 | 2.5 | 0.14 | 1.1 | 0.11 | 0.018 | 0.065 | 1.1 | 0.18 | 0.056 | 0.44 | 0.044 | 0.0072 | 0.026 | 0.44 | 0.072 |
| 48 | 2.6 | 0.13 | 0.087 | 0.050 | 0.033 | ||||||||||
| 72 | 2.0 | ||||||||||||||
| 96 | 2.0 |