Table 5.
For male study participants: Anthropometric and biochemical characteristics (mean (±SD) or median (25th to 75th percentile) data) according to six different alcohol consumption groups.
| Variable | Groups of total alcohol consumption |
|||||||
|---|---|---|---|---|---|---|---|---|
| Male | No consumption 0 g/d ethanol |
Very low consumption > 0.0 - 12.0 g/d ethanol |
Low consumption > 12.0 - 24.0 g/d ethanol |
Medium consumption > 24.0 - 36.0 g/d ethanol |
High consumption > 36.0 - 48.0 g/d ethanol |
Very high consumption > 48.0 g/d ethanol |
Pa | FDR-Pb |
| N | 312 | 188 | 104 | 121 | 82 | 117 | - | - |
| Age (years) | 61 ± 11.2 | 61.7 ± 11.0 | 61.5 ± 11.1 | 64.5 ± 9.71 | 61.8 ± 10.5 | 61.2 ± 9.09 | <0.001 | 0.001 |
| BMI (kg/m2) | 27.6 ± 4.2 | 27.4 ± 3.74 | 27.5 ± 3.65 | 27.6 ± 3.39 | 27.4 ± 3.26 | 28.0 ± 3.77 | 0.405 | 0.450 |
| LDL-cholesterol (mg/dl) | 113 ± 33.6 | 114.0 ± 32.0 | 116.0 ± 31.7 | 110.0 ± 30.8 | 117.0 ± 37.0 | 113.0 ± 33.0 | 0.222 | 0.277 |
| HDL-Cholesterol (mg/dl) | 34.6 ± 9.2 | 36.2 ± 9.26 | 37.5 ± 9.88 | 37.9 ± 9.66 | 39.1 ± 9.83 | 39.1 ± 10.8 | <0.001 | <0.001 |
| Apolipoprotein A-I (mg/dl) | 119.0 ±21.1 | 123.0 ± 21.5 | 127.0 ± 23.2 | 126.0 ± 21.7 | 129.0 ± 22.5 | 131.0 ± 25.0 | <0.001 | <0.001 |
| Apolipoprotein A-II (mg/dl) | 38.9 ±8.46 | 40.8 ± 9.95 | 42.8 ± 8.8 | 40.6 ± 8.5 | 43.2 ± 9.84 | 43.8 ± 10.3 | <0.001 | <0.001 |
| Triglycerides (mg/dl) | 155 (111-202) | 142 (105-195) | 160 (119-216) | 138 (111-184) | 146 (114-196) | 152 (112-220) | 0.001 | 0.002 |
| Fasting glucose (mg/dl) | 102 (93.6-121) | 101 (92.6-116) | 104 (95.4-121) | 104 (95.3-118) | 103 (96.6-115) | 105 (97.2-119) | 0.133 | 0.178 |
| HbA1c (%) | 6.47 ± 1.43 | 6.15 ± 1.12 | 6.23 ± 1.37 | 6.17 ± 1.11 | 6.23 ± 1.04 | 6.22 ± 1.08 | <0.001 | <0.001 |
| Systolic blood pressure (mmHg) | 140.0 ± 24.2 | 142.0 ± 23.5 | 144.0 ± 22.7 | 141.0 ± 22.2 | 139.0 ± 21.7 | 140.0 ± 22.8 | 0.264 | 0.310 |
| Diastolic blood pressure (mmHg) | 80.9 ± 11.7 | 82.5 ± 11.9 | 82.5 ± 11.5 | 82.2 ± 11.2 | 80.8 ± 10.5 | 81.2 ± 10.6 | 0.100 | 0.152 |
| eGFR (ml/min/1.73 m2) | 82.5 ± 21.8 | 84.3 ± 19.6 | 84.8 ± 20.0 | 81.6 ± 18.5 | 85.8 ± 17.9 | 86.8 ± 18.5 | 0.004 | 0.009 |
| hsCRP (mg/L) | 3.6 (1.57-8.85) | 2.87 (1.04-7.68) | 2.78 (1.15-8.35) | 2.79 (1.11-6.62) | 3.47 (1.25-9.98) | 4.3 (1.41-9.72) | 0.002 | 0.004 |
| NT-pro-BNP (pg/mL) | 302 (100-890) | 246 (89.8-696) | 292 (94-1010) | 320 (107-937) | 322 (88-967) | 276 (108-874) | 0.429 | 0.451 |
| Coronary artery disease (%) | 86.8 | 83.8 | 80.5 | 82.7 | 82.5 | 80.6 | 0.087 | 0.146 |
| Hypertension (%) | 72.2 | 70.5 | 75.2 | 68.7 | 69.6 | 71 | 0.591 | 0.591 |
| Diabetes mellitus type 2 (%) | 44.3 | 36.7 | 39.7 | 40.3 | 37.8 | 37.3 | 0.107 | 0.152 |
| Smoking (pack years) | 17.5 (1-37.5) | 10.1 (0.15-30) | 18.8 (3.15-35) | 13.8 (1-30.5) | 16 (3.4-30) | 20 (5-45) | 0.001 | 0.002 |
| Smoking (active/ex/ never, %) | 29.4/47.5/23.1 | 22.3/48.8/28.9 | 27.9/51.9/20.2 | 15.7/61.7/22.7 | 24.9/54.4/20.7 | 35/46.5/18.5 | <0.001 | <0.001 |
a
ANOVA (non-normally distributed variables were analysed by Kruskal-Wallis rank sum test) or Chi square test.
b
p value after FDR correction.